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European Organization for Caries Research Workshop: Methodology for Determination of Potentially Available Fluoride in Toothpastes

Research output: Contribution to journalReview article

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European Organization for Caries Research Workshop : Methodology for Determination of Potentially Available Fluoride in Toothpastes. / ORCA Fluoride in Toothpaste Analysis Work Group .

In: Caries research, Vol. 53, No. 2, 01.01.2019, p. 119-136.

Research output: Contribution to journalReview article

Harvard

ORCA Fluoride in Toothpaste Analysis Work Group  2019, 'European Organization for Caries Research Workshop: Methodology for Determination of Potentially Available Fluoride in Toothpastes', Caries research, vol. 53, no. 2, pp. 119-136. https://doi.org/10.1159/000490196

APA

ORCA Fluoride in Toothpaste Analysis Work Group  (2019). European Organization for Caries Research Workshop: Methodology for Determination of Potentially Available Fluoride in Toothpastes. Caries research, 53(2), 119-136. https://doi.org/10.1159/000490196

Vancouver

ORCA Fluoride in Toothpaste Analysis Work Group . European Organization for Caries Research Workshop: Methodology for Determination of Potentially Available Fluoride in Toothpastes. Caries research. 2019 Jan 1;53(2):119-136. https://doi.org/10.1159/000490196

Author

ORCA Fluoride in Toothpaste Analysis Work Group . / European Organization for Caries Research Workshop : Methodology for Determination of Potentially Available Fluoride in Toothpastes. In: Caries research. 2019 ; Vol. 53, No. 2. pp. 119-136.

Bibtex Download

@article{1cd884fcfba04b3fa717ce08a7052a70,
title = "European Organization for Caries Research Workshop: Methodology for Determination of Potentially Available Fluoride in Toothpastes",
abstract = "Toothpastes are the most universally accepted form of fluoride delivery for caries prevention. To provide anti-caries benefits, they must be able to release fluoride during the time of tooth brushing or post brushing into the oral cavity. However, there is no standard accepted procedure to measure how much fluoride in a toothpaste may be (bio) available for release. The European Organization for Caries Research proposed and supported a workshop with experts in fluoride analysis in toothpastes and representatives from industry. The objective of the workshop was to discuss issues surrounding fluoride analysis in toothpaste and reach consensus on terminology and best practices, wherever the available evidence allowed it. Participants received a background paper and heard presentations followed by structured discussion to define the problem. The group also reviewed evidence on the validity, reliability and feasibility of each technique (namely chromatography and fluoride electroanalysis) and discussed their strengths and limitations. Participants were able to reach a consensus on terminology and were also able to identify and summarize the advantages and disadvantages of each technique. However, they agreed that most currently available methods were developed for regulatory agencies several decades ago, utilizing the best available data from clinical trials then, but require to be updated. They also agreed that although significant advances to our understanding of the mechanism of action of fluoride in toothpaste have been achieved over the past 4 decades, this clearly is an extraordinarily complex subject and more work remains to be done.",
keywords = "Available Fluoride, Fluoride, Fluoride Analysis, Research Workshop, Toothpastes",
author = "ORCA Fluoride in Toothpaste Analysis Work Group  and Martinez-Mier, {E. Angeles} and Tenuta, {Livia Maria Andal{\'o}} and Carey, {Clifton M.} and Cury, {Jaime A.} and {van Loveren}, Cor and Ekstrand, {Kim Rud} and Carolina Ganss and Andreas Schulte and Arif Baig and Habib Benzian and Peter Bottenberg and Buijs, {Mark J.} and Alan Ceresa and Carvalho, {Joana Christina} and Roger Ellwood and Carlos Gonz{\'a}lez-Cabezas and Christopher Holmgren and Michael Knapp and Frank Lippert and Andrew Joiner and Manton, {David J.} and Stefania Martignon and Stephen Mason and Anahita Jablonski-Momeni and Walter Plett and Chris Rahiotis and F{\'a}bio Sampaio and Zero, {Domenick T.}",
year = "2019",
month = "1",
day = "1",
doi = "10.1159/000490196",
language = "English",
volume = "53",
pages = "119--136",
journal = "Caries research",
issn = "0008-6568",
publisher = "S. Karger AG",
number = "2",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - European Organization for Caries Research Workshop

T2 - Methodology for Determination of Potentially Available Fluoride in Toothpastes

AU - ORCA Fluoride in Toothpaste Analysis Work Group 

AU - Martinez-Mier, E. Angeles

AU - Tenuta, Livia Maria Andaló

AU - Carey, Clifton M.

AU - Cury, Jaime A.

AU - van Loveren, Cor

AU - Ekstrand, Kim Rud

AU - Ganss, Carolina

AU - Schulte, Andreas

AU - Baig, Arif

AU - Benzian, Habib

AU - Bottenberg, Peter

AU - Buijs, Mark J.

AU - Ceresa, Alan

AU - Carvalho, Joana Christina

AU - Ellwood, Roger

AU - González-Cabezas, Carlos

AU - Holmgren, Christopher

AU - Knapp, Michael

AU - Lippert, Frank

AU - Joiner, Andrew

AU - Manton, David J.

AU - Martignon, Stefania

AU - Mason, Stephen

AU - Jablonski-Momeni, Anahita

AU - Plett, Walter

AU - Rahiotis, Chris

AU - Sampaio, Fábio

AU - Zero, Domenick T.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Toothpastes are the most universally accepted form of fluoride delivery for caries prevention. To provide anti-caries benefits, they must be able to release fluoride during the time of tooth brushing or post brushing into the oral cavity. However, there is no standard accepted procedure to measure how much fluoride in a toothpaste may be (bio) available for release. The European Organization for Caries Research proposed and supported a workshop with experts in fluoride analysis in toothpastes and representatives from industry. The objective of the workshop was to discuss issues surrounding fluoride analysis in toothpaste and reach consensus on terminology and best practices, wherever the available evidence allowed it. Participants received a background paper and heard presentations followed by structured discussion to define the problem. The group also reviewed evidence on the validity, reliability and feasibility of each technique (namely chromatography and fluoride electroanalysis) and discussed their strengths and limitations. Participants were able to reach a consensus on terminology and were also able to identify and summarize the advantages and disadvantages of each technique. However, they agreed that most currently available methods were developed for regulatory agencies several decades ago, utilizing the best available data from clinical trials then, but require to be updated. They also agreed that although significant advances to our understanding of the mechanism of action of fluoride in toothpaste have been achieved over the past 4 decades, this clearly is an extraordinarily complex subject and more work remains to be done.

AB - Toothpastes are the most universally accepted form of fluoride delivery for caries prevention. To provide anti-caries benefits, they must be able to release fluoride during the time of tooth brushing or post brushing into the oral cavity. However, there is no standard accepted procedure to measure how much fluoride in a toothpaste may be (bio) available for release. The European Organization for Caries Research proposed and supported a workshop with experts in fluoride analysis in toothpastes and representatives from industry. The objective of the workshop was to discuss issues surrounding fluoride analysis in toothpaste and reach consensus on terminology and best practices, wherever the available evidence allowed it. Participants received a background paper and heard presentations followed by structured discussion to define the problem. The group also reviewed evidence on the validity, reliability and feasibility of each technique (namely chromatography and fluoride electroanalysis) and discussed their strengths and limitations. Participants were able to reach a consensus on terminology and were also able to identify and summarize the advantages and disadvantages of each technique. However, they agreed that most currently available methods were developed for regulatory agencies several decades ago, utilizing the best available data from clinical trials then, but require to be updated. They also agreed that although significant advances to our understanding of the mechanism of action of fluoride in toothpaste have been achieved over the past 4 decades, this clearly is an extraordinarily complex subject and more work remains to be done.

KW - Available Fluoride

KW - Fluoride

KW - Fluoride Analysis

KW - Research Workshop

KW - Toothpastes

UR - http://www.scopus.com/inward/record.url?scp=85062083587&partnerID=8YFLogxK

U2 - 10.1159/000490196

DO - 10.1159/000490196

M3 - Review article

C2 - 30041245

AN - SCOPUS:85062083587

VL - 53

SP - 119

EP - 136

JO - Caries research

JF - Caries research

SN - 0008-6568

IS - 2

ER -

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