Evaluating hyaluronic acid dermal fillers: A critique of current characterization methods

Ploymanee Wongprasert; Cécile A. Dreiss; Gillian Murray

doi:10.1111/dth.15453

Evaluating hyaluronic acid dermal fillers: A critique of current characterization methods

Ploymanee Wongprasert, Cécile A. Dreiss, Gillian Murray

Institute of Pharmaceutical Science

b King's College London Institute of Pharmaceutical Science , London , UK.

Research output: Contribution to journal › Review article › peer-review

32 Citations (Scopus)

607 Downloads (Pure)

Abstract

Soft-tissue augmentation has gained much popularity in recent years. Hyaluronic acid (HA) based dermal fillers; a non-permanent injectable device, can restore volume loss, fill fine lines and wrinkles and add curves and contours. HA based dermal fillers entered the non-surgical treatment market in the late 1990s, however there is a lack of data and literature comparing the range of products and detailing the complexities of these products and how it relates to tissue performance. Measuring the physico-chemical properties of these dermal fillers provide key parameters to predict their performance after injection into the body. This article reviews the currently reported methods and parameters used to characterize dermal fillers. The review of these methods and data from the literature provides a useful guide to clinicians and injectors in selecting the optimal product suitable for the needs of each patient.

Original language	English
Article number	e15453
Journal	Dermatologic Therapy
Volume	35
Issue number	6
Early online date	5 Apr 2022
DOIs	https://doi.org/10.1111/dth.15453
Publication status	Published - Jun 2022

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10.1111/dth.15453Licence: CC BY

Evaluating hyaluronic acid _WONGPRASERT_Publishedonline16March2022_GOLD VoR (CC BY)Final published version, 1.41 MBLicence: CC BY

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title = "Evaluating hyaluronic acid dermal fillers: A critique of current characterization methods",

abstract = "Soft-tissue augmentation has gained much popularity in recent years. Hyaluronic acid (HA) based dermal fillers; a non-permanent injectable device, can restore volume loss, fill fine lines and wrinkles and add curves and contours. HA based dermal fillers entered the non-surgical treatment market in the late 1990s, however there is a lack of data and literature comparing the range of products and detailing the complexities of these products and how it relates to tissue performance. Measuring the physico-chemical properties of these dermal fillers provide key parameters to predict their performance after injection into the body. This article reviews the currently reported methods and parameters used to characterize dermal fillers. The review of these methods and data from the literature provides a useful guide to clinicians and injectors in selecting the optimal product suitable for the needs of each patient.",

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AB - Soft-tissue augmentation has gained much popularity in recent years. Hyaluronic acid (HA) based dermal fillers; a non-permanent injectable device, can restore volume loss, fill fine lines and wrinkles and add curves and contours. HA based dermal fillers entered the non-surgical treatment market in the late 1990s, however there is a lack of data and literature comparing the range of products and detailing the complexities of these products and how it relates to tissue performance. Measuring the physico-chemical properties of these dermal fillers provide key parameters to predict their performance after injection into the body. This article reviews the currently reported methods and parameters used to characterize dermal fillers. The review of these methods and data from the literature provides a useful guide to clinicians and injectors in selecting the optimal product suitable for the needs of each patient.

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Evaluating hyaluronic acid dermal fillers: A critique of current characterization methods

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