Expanding Horizons for Abdominal Aortic Aneurysms

Rachel C. Rolph; Matthew Waltham; Alberto Smith; Helena Kuivaniemi

doi:10.12945/j.aorta.2015.14-041

Expanding Horizons for Abdominal Aortic Aneurysms

Rachel C. Rolph^*
, Matthew Waltham
, Alberto Smith
, Helena Kuivaniemi

^*Corresponding author for this work

Vascular Risk & Surgery

St Thomas' Hospital
Academic Department of Surgery
Sigfried and Janet Weis Center for Research
Temple University School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Recent technological advances have allowed researchers to interrogate the genetic basis of abdominal aortic aneurysms in great detail. The results from these studies are expected to transform our understanding of this complex disease with both multiple genetic and environmental risk factors. Clinicians need to keep abreast of these genetic findings and understand the implications for their practice. Patients will become increasingly informed on genetic risk, and a new era of individualized risk assessment for AAA is just beginning. This brief update aims to provide the clinician with a succinct précis of the recent progress in this area.

Original language	English
Pages (from-to)	9-15
Number of pages	7
Journal	AORTA
Volume	3
Issue number	1
DOIs	https://doi.org/10.12945/j.aorta.2015.14-041
Publication status	Published - 24 Feb 2015

Keywords

Aneurysm
Association Studies
DNA Sequencing
Genetic
Risk score

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10.12945/j.aorta.2015.14-041

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abstract = "Recent technological advances have allowed researchers to interrogate the genetic basis of abdominal aortic aneurysms in great detail. The results from these studies are expected to transform our understanding of this complex disease with both multiple genetic and environmental risk factors. Clinicians need to keep abreast of these genetic findings and understand the implications for their practice. Patients will become increasingly informed on genetic risk, and a new era of individualized risk assessment for AAA is just beginning. This brief update aims to provide the clinician with a succinct pr{\'e}cis of the recent progress in this area.",

keywords = "Aneurysm, Association Studies, DNA Sequencing, Genetic, Risk score",

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AU - Smith, Alberto

AU - Kuivaniemi, Helena

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AB - Recent technological advances have allowed researchers to interrogate the genetic basis of abdominal aortic aneurysms in great detail. The results from these studies are expected to transform our understanding of this complex disease with both multiple genetic and environmental risk factors. Clinicians need to keep abreast of these genetic findings and understand the implications for their practice. Patients will become increasingly informed on genetic risk, and a new era of individualized risk assessment for AAA is just beginning. This brief update aims to provide the clinician with a succinct précis of the recent progress in this area.

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KW - Association Studies

KW - DNA Sequencing

KW - Genetic

KW - Risk score

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Expanding Horizons for Abdominal Aortic Aneurysms

Abstract

Keywords

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