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Extracorporeal Membrane Oxygenation for Respiratory Failure

Research output: Contribution to journalReview article

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Extracorporeal Membrane Oxygenation for Respiratory Failure. / Quintel, Michael; Bartlett, Robert H.; Grocott, Michael P.W.; Combes, Alain; Ranieri, Marco V.; Baiocchi, Massimo; Nava, Stefano; Brodie, Daniel; Camporota, Luigi; Vasques, Francesco; Busana, Mattia; Marini, John J.; Gattinoni, Luciano.

In: Anesthesiology, 01.01.2020, p. 1257-1276.

Research output: Contribution to journalReview article

Harvard

Quintel, M, Bartlett, RH, Grocott, MPW, Combes, A, Ranieri, MV, Baiocchi, M, Nava, S, Brodie, D, Camporota, L, Vasques, F, Busana, M, Marini, JJ & Gattinoni, L 2020, 'Extracorporeal Membrane Oxygenation for Respiratory Failure', Anesthesiology, pp. 1257-1276. https://doi.org/10.1097/ALN.0000000000003221

APA

Quintel, M., Bartlett, R. H., Grocott, M. P. W., Combes, A., Ranieri, M. V., Baiocchi, M., Nava, S., Brodie, D., Camporota, L., Vasques, F., Busana, M., Marini, J. J., & Gattinoni, L. (Accepted/In press). Extracorporeal Membrane Oxygenation for Respiratory Failure. Anesthesiology, 1257-1276. https://doi.org/10.1097/ALN.0000000000003221

Vancouver

Quintel M, Bartlett RH, Grocott MPW, Combes A, Ranieri MV, Baiocchi M et al. Extracorporeal Membrane Oxygenation for Respiratory Failure. Anesthesiology. 2020 Jan 1;1257-1276. https://doi.org/10.1097/ALN.0000000000003221

Author

Quintel, Michael ; Bartlett, Robert H. ; Grocott, Michael P.W. ; Combes, Alain ; Ranieri, Marco V. ; Baiocchi, Massimo ; Nava, Stefano ; Brodie, Daniel ; Camporota, Luigi ; Vasques, Francesco ; Busana, Mattia ; Marini, John J. ; Gattinoni, Luciano. / Extracorporeal Membrane Oxygenation for Respiratory Failure. In: Anesthesiology. 2020 ; pp. 1257-1276.

Bibtex Download

@article{92077b0fa3b9481ebfeeb16350ff53d3,
title = "Extracorporeal Membrane Oxygenation for Respiratory Failure",
abstract = "This review focuses on the use of veno-venous extracorporeal membrane oxygenation for respiratory failure across all blood flow ranges. Starting with a short overview of historical development, aspects of the physiology of gas exchange (i.e., oxygenation and decarboxylation) during extracorporeal circulation are discussed. The mechanisms of phenomena such as recirculation and shunt playing an important role in daily clinical practice are explained. Treatment of refractory and symptomatic hypoxemic respiratory failure (e.g., acute respiratory distress syndrome [ARDS]) currently represents the main indication for high-flow veno-venous-extracorporeal membrane oxygenation. On the other hand, lower-flow extracorporeal carbon dioxide removal might potentially help to avoid or attenuate ventilator-induced lung injury by allowing reduction of the energy load (i.e., driving pressure, mechanical power) transmitted to the lungs during mechanical ventilation or spontaneous ventilation. In the latter context, extracorporeal carbon dioxide removal plays an emerging role in the treatment of chronic obstructive pulmonary disease patients during acute exacerbations. Both applications of extracorporeal lung support raise important ethical considerations, such as likelihood of ultimate futility and end-of-life decision-making. The review concludes with a brief overview of potential technical developments and persistent challenges.",
author = "Michael Quintel and Bartlett, {Robert H.} and Grocott, {Michael P.W.} and Alain Combes and Ranieri, {Marco V.} and Massimo Baiocchi and Stefano Nava and Daniel Brodie and Luigi Camporota and Francesco Vasques and Mattia Busana and Marini, {John J.} and Luciano Gattinoni",
year = "2020",
month = jan,
day = "1",
doi = "10.1097/ALN.0000000000003221",
language = "English",
pages = "1257--1276",
journal = "Anesthesiology",
issn = "0003-3022",
publisher = "Lippincott Williams and Wilkins",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Extracorporeal Membrane Oxygenation for Respiratory Failure

AU - Quintel, Michael

AU - Bartlett, Robert H.

AU - Grocott, Michael P.W.

AU - Combes, Alain

AU - Ranieri, Marco V.

AU - Baiocchi, Massimo

AU - Nava, Stefano

AU - Brodie, Daniel

AU - Camporota, Luigi

AU - Vasques, Francesco

AU - Busana, Mattia

AU - Marini, John J.

AU - Gattinoni, Luciano

PY - 2020/1/1

Y1 - 2020/1/1

N2 - This review focuses on the use of veno-venous extracorporeal membrane oxygenation for respiratory failure across all blood flow ranges. Starting with a short overview of historical development, aspects of the physiology of gas exchange (i.e., oxygenation and decarboxylation) during extracorporeal circulation are discussed. The mechanisms of phenomena such as recirculation and shunt playing an important role in daily clinical practice are explained. Treatment of refractory and symptomatic hypoxemic respiratory failure (e.g., acute respiratory distress syndrome [ARDS]) currently represents the main indication for high-flow veno-venous-extracorporeal membrane oxygenation. On the other hand, lower-flow extracorporeal carbon dioxide removal might potentially help to avoid or attenuate ventilator-induced lung injury by allowing reduction of the energy load (i.e., driving pressure, mechanical power) transmitted to the lungs during mechanical ventilation or spontaneous ventilation. In the latter context, extracorporeal carbon dioxide removal plays an emerging role in the treatment of chronic obstructive pulmonary disease patients during acute exacerbations. Both applications of extracorporeal lung support raise important ethical considerations, such as likelihood of ultimate futility and end-of-life decision-making. The review concludes with a brief overview of potential technical developments and persistent challenges.

AB - This review focuses on the use of veno-venous extracorporeal membrane oxygenation for respiratory failure across all blood flow ranges. Starting with a short overview of historical development, aspects of the physiology of gas exchange (i.e., oxygenation and decarboxylation) during extracorporeal circulation are discussed. The mechanisms of phenomena such as recirculation and shunt playing an important role in daily clinical practice are explained. Treatment of refractory and symptomatic hypoxemic respiratory failure (e.g., acute respiratory distress syndrome [ARDS]) currently represents the main indication for high-flow veno-venous-extracorporeal membrane oxygenation. On the other hand, lower-flow extracorporeal carbon dioxide removal might potentially help to avoid or attenuate ventilator-induced lung injury by allowing reduction of the energy load (i.e., driving pressure, mechanical power) transmitted to the lungs during mechanical ventilation or spontaneous ventilation. In the latter context, extracorporeal carbon dioxide removal plays an emerging role in the treatment of chronic obstructive pulmonary disease patients during acute exacerbations. Both applications of extracorporeal lung support raise important ethical considerations, such as likelihood of ultimate futility and end-of-life decision-making. The review concludes with a brief overview of potential technical developments and persistent challenges.

UR - http://www.scopus.com/inward/record.url?scp=85083971711&partnerID=8YFLogxK

U2 - 10.1097/ALN.0000000000003221

DO - 10.1097/ALN.0000000000003221

M3 - Review article

C2 - 32149776

AN - SCOPUS:85083971711

SP - 1257

EP - 1276

JO - Anesthesiology

JF - Anesthesiology

SN - 0003-3022

ER -

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