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Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine

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Extracting new information from old waveforms : Symmetric projection attractor reconstruction: Where maths meets medicine. / Nandi, Manasi; Aston, Philip J.

In: Experimental Physiology, Vol. 105, No. 9, 01.09.2020, p. 1444-1451.

Research output: Contribution to journalArticle

Harvard

Nandi, M & Aston, PJ 2020, 'Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine', Experimental Physiology, vol. 105, no. 9, pp. 1444-1451. https://doi.org/10.1113/EP087873

APA

Nandi, M., & Aston, P. J. (2020). Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine. Experimental Physiology, 105(9), 1444-1451. https://doi.org/10.1113/EP087873

Vancouver

Nandi M, Aston PJ. Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine. Experimental Physiology. 2020 Sep 1;105(9):1444-1451. https://doi.org/10.1113/EP087873

Author

Nandi, Manasi ; Aston, Philip J. / Extracting new information from old waveforms : Symmetric projection attractor reconstruction: Where maths meets medicine. In: Experimental Physiology. 2020 ; Vol. 105, No. 9. pp. 1444-1451.

Bibtex Download

@article{22b9f5d3eb824ce3a066045d1fc86b5e,
title = "Extracting new information from old waveforms: Symmetric projection attractor reconstruction: Where maths meets medicine",
abstract = "New Findings: What is the topic of this review? Symmetric Projection Attractor Reconstruction (SPAR) is a relatively new mathematical method that can extract additional information pertaining to the morphology and variability of physiological waveforms, such as arterial pulse pressure. Herein, we describe the potential utility of the method for more sensitive quantification of cardiovascular changes. What advances does it highlight? We use a simple example of a human tilt table to illustrate these concepts. SPAR can be used on any approximately periodic waveform and may add value to experimental and clinical settings, where such signals are collected routinely. Abstract: Periodic physiological waveform data, such as blood pressure, pulse oximetry and ECG, are routinely sampled between 100 and 1000 Hz in preclinical research and in the clinical setting from a wide variety of implantable, bedside and wearable monitoring devices. Despite the underlying numerical waveform data being captured at such high fidelity, conventional analysis tends to reside in reporting only averages of minimum, maximum, amplitude and rate, as single point averages. Although these averages are undoubtedly of value, simplification of the data in this way means that most of the available numerical data are discarded. In turn, this may lead to subtle physiological changes being missed when investigating the cardiovascular system over time. We have developed a mathematical method (symmetric projection attractor reconstruction) that uses all the numerical data, replotting and revisualizing them in a manner that allows unique quantification of multiple changes in waveform morphology and variability. We propose that the additional quantification of these features will allow the complex behaviour of the cardiovascular system to be mapped more sensitively in different physiological and pathophysiological settings.",
keywords = "arterial pulse, attractor reconstruction, automated feature detection, data sciences, heart rate variability, waveform morphology, waveform variability",
author = "Manasi Nandi and Aston, {Philip J.}",
year = "2020",
month = sep,
day = "1",
doi = "10.1113/EP087873",
language = "English",
volume = "105",
pages = "1444--1451",
journal = "Experimental Physiology",
issn = "0958-0670",
publisher = "Wiley-Blackwell",
number = "9",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Extracting new information from old waveforms

T2 - Symmetric projection attractor reconstruction: Where maths meets medicine

AU - Nandi, Manasi

AU - Aston, Philip J.

PY - 2020/9/1

Y1 - 2020/9/1

N2 - New Findings: What is the topic of this review? Symmetric Projection Attractor Reconstruction (SPAR) is a relatively new mathematical method that can extract additional information pertaining to the morphology and variability of physiological waveforms, such as arterial pulse pressure. Herein, we describe the potential utility of the method for more sensitive quantification of cardiovascular changes. What advances does it highlight? We use a simple example of a human tilt table to illustrate these concepts. SPAR can be used on any approximately periodic waveform and may add value to experimental and clinical settings, where such signals are collected routinely. Abstract: Periodic physiological waveform data, such as blood pressure, pulse oximetry and ECG, are routinely sampled between 100 and 1000 Hz in preclinical research and in the clinical setting from a wide variety of implantable, bedside and wearable monitoring devices. Despite the underlying numerical waveform data being captured at such high fidelity, conventional analysis tends to reside in reporting only averages of minimum, maximum, amplitude and rate, as single point averages. Although these averages are undoubtedly of value, simplification of the data in this way means that most of the available numerical data are discarded. In turn, this may lead to subtle physiological changes being missed when investigating the cardiovascular system over time. We have developed a mathematical method (symmetric projection attractor reconstruction) that uses all the numerical data, replotting and revisualizing them in a manner that allows unique quantification of multiple changes in waveform morphology and variability. We propose that the additional quantification of these features will allow the complex behaviour of the cardiovascular system to be mapped more sensitively in different physiological and pathophysiological settings.

AB - New Findings: What is the topic of this review? Symmetric Projection Attractor Reconstruction (SPAR) is a relatively new mathematical method that can extract additional information pertaining to the morphology and variability of physiological waveforms, such as arterial pulse pressure. Herein, we describe the potential utility of the method for more sensitive quantification of cardiovascular changes. What advances does it highlight? We use a simple example of a human tilt table to illustrate these concepts. SPAR can be used on any approximately periodic waveform and may add value to experimental and clinical settings, where such signals are collected routinely. Abstract: Periodic physiological waveform data, such as blood pressure, pulse oximetry and ECG, are routinely sampled between 100 and 1000 Hz in preclinical research and in the clinical setting from a wide variety of implantable, bedside and wearable monitoring devices. Despite the underlying numerical waveform data being captured at such high fidelity, conventional analysis tends to reside in reporting only averages of minimum, maximum, amplitude and rate, as single point averages. Although these averages are undoubtedly of value, simplification of the data in this way means that most of the available numerical data are discarded. In turn, this may lead to subtle physiological changes being missed when investigating the cardiovascular system over time. We have developed a mathematical method (symmetric projection attractor reconstruction) that uses all the numerical data, replotting and revisualizing them in a manner that allows unique quantification of multiple changes in waveform morphology and variability. We propose that the additional quantification of these features will allow the complex behaviour of the cardiovascular system to be mapped more sensitively in different physiological and pathophysiological settings.

KW - arterial pulse

KW - attractor reconstruction

KW - automated feature detection

KW - data sciences

KW - heart rate variability

KW - waveform morphology

KW - waveform variability

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U2 - 10.1113/EP087873

DO - 10.1113/EP087873

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VL - 105

SP - 1444

EP - 1451

JO - Experimental Physiology

JF - Experimental Physiology

SN - 0958-0670

IS - 9

ER -

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