F-18 FDG PET/CT imaging of follicular dendritic cell sarcoma of the mediastinum

Manil Subesinghe, Jonathan T Smith, Fahmid U Chowdhury

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A 52-year-old female smoker presenting with unexplained weight loss underwent CT and FDG PET/CT imaging, which demonstrated an extremely hypermetabolic mediastinal mass with calcification, necrosis, and features of local invasiveness. Mediastinoscopy and biopsy were followed by successful surgical resection of an encapsulated mass showing the typical histologic features of follicular dendritic cell sarcoma (FDCS). FDCS of the mediastinum is a rare neoplasm arising from accessory cells of the immune system. Integrated FDG PET/CT of mediastinal FDCS highlights the importance of histologic assessment of mediastinal tumors that may seem unresectable on initial imaging.

Original languageEnglish
Pages (from-to)204-5
Number of pages2
JournalClinical Nuclear Medicine
Volume37
Issue number2
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Dendritic Cell Sarcoma, Follicular
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Mediastinal Neoplasms
  • Middle Aged
  • Multimodal Imaging
  • Positron-Emission Tomography
  • Tomography, X-Ray Computed
  • Case Reports
  • Journal Article

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