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Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Research output: Contribution to journalArticlepeer-review

Jessica Fleminger, Kate Duhig, Paul T Seed, Peter Brocklehurst, Marcus Green, Edmund Juszczak, Neil Marlow, Andrew Shennan, Lucy Chappell

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalPregnancy Hypertension
Volume26
Early online date13 Oct 2021
DOIs
E-pub ahead of print13 Oct 2021
Published1 Dec 2021

Bibliographical note

Funding Information: The trial was funded by the National Institute for Health Research Health Technology Assessment Programme (Reference 12/25/03). Publisher Copyright: © 2021

King's Authors

Abstract

This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks' gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.

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