FDG PET-CT in rheumatological diseases

Manil Subesinghe; Shaheel Bhuva; Nikita Arumalla; Andrew Cope; David D'Cruz; Sujith Subesinghe

doi:10.1093/rheumatology/keab675

FDG PET-CT in rheumatological diseases

Manil Subesinghe, Shaheel Bhuva, Nikita Arumalla, Andrew Cope, David D'Cruz, Sujith Subesinghe

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

2-deoxy-2[¹⁸F]fluoro-D-glucose (FDG) positron emission tomography-computed tomography (PET-CT) has revolutionised oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT, also occur in a wide range of inflammatory cells; exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article, we will describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case.

Original language	English
Article number	keab675
Journal	Rheumatology
Early online date	31 Aug 2021
DOIs	https://doi.org/10.1093/rheumatology/keab675
Publication status	E-pub ahead of print - 31 Aug 2021

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title = "FDG PET-CT in rheumatological diseases",

abstract = "2-deoxy-2[18F]fluoro-D-glucose (FDG) positron emission tomography-computed tomography (PET-CT) has revolutionised oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT, also occur in a wide range of inflammatory cells; exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article, we will describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case.",

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T1 - FDG PET-CT in rheumatological diseases

AU - Subesinghe, Manil

AU - Bhuva, Shaheel

AU - Arumalla, Nikita

AU - Cope, Andrew

AU - D'Cruz, David

AU - Subesinghe, Sujith

PY - 2021/8/31

Y1 - 2021/8/31

N2 - 2-deoxy-2[18F]fluoro-D-glucose (FDG) positron emission tomography-computed tomography (PET-CT) has revolutionised oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT, also occur in a wide range of inflammatory cells; exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article, we will describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case.

AB - 2-deoxy-2[18F]fluoro-D-glucose (FDG) positron emission tomography-computed tomography (PET-CT) has revolutionised oncological imaging. The cellular processes that make cancer cells visible on FDG PET-CT, also occur in a wide range of inflammatory cells; exploiting this phenomenon has led to a growth of evidence supporting the use of FDG PET-CT in a wide range of infective and inflammatory diseases. Rheumatological diseases can affect multiple sites within the musculoskeletal system alongside multi-organ extra-articular disease manifestations. Inflammation is central to these diseases, making FDG PET-CT a logical choice. In this review article, we will describe the various applications of FDG PET-CT in rheumatological diseases using illustrative examples to highlight the beneficial role of FDG PET-CT in each case.

U2 - 10.1093/rheumatology/keab675

DO - 10.1093/rheumatology/keab675

M3 - Article

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SN - 1462-0324

JO - Rheumatology

JF - Rheumatology

M1 - keab675

ER -

FDG PET-CT in rheumatological diseases

Abstract

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