FDG PET-CT: Need for vigilance in patients treated with bleomycin

TY - JOUR

T1 - FDG PET-CT

T2 - Need for vigilance in patients treated with bleomycin

AU - Paschali, Anna N

AU - Gnanasegaran, Gopinath

AU - Cook, Gary J

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/nuclear medicine specialists be aware of the features of this potentially treatable condition so that treatment can be instigated during an early reversible phase before pulmonary damage has occurred. Herein, we report two cases of bleomycin toxicity featuring different patterns on the treatment-response assessment FDG PET-CT scan.

AB - Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/nuclear medicine specialists be aware of the features of this potentially treatable condition so that treatment can be instigated during an early reversible phase before pulmonary damage has occurred. Herein, we report two cases of bleomycin toxicity featuring different patterns on the treatment-response assessment FDG PET-CT scan.

KW - Bleomycin

KW - FDG

KW - Lung toxicity

KW - PET-CT

UR - http://www.scopus.com/inward/record.url?scp=85016413450&partnerID=8YFLogxK

U2 - 10.4103/0972-3919.202242

DO - 10.4103/0972-3919.202242

M3 - Article

AN - SCOPUS:85016413450

SN - 0972-3919

VL - 32

SP - 122

EP - 124

JO - Indian Journal of Nuclear Medicine

JF - Indian Journal of Nuclear Medicine

IS - 2

ER -