Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

TY - JOUR

T1 - Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

AU - Peek, Mirjam C.L.

AU - Zada, Ali

AU - Ahmed, Muneer

AU - Baker, Rose

AU - Sekino, Masaki

AU - Kusakabe, Moriaki

AU - Douek, Michael

PY - 2018/1/16

Y1 - 2018/1/16

N2 - Aims The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8±400.2, mean±SD) with unequal variances (p<0.001) and the butterfly marker showed the smallest mean artefact-volume (11.1±2.3 cm3) with a significant difference between markers (p=0.049). Conclusion Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.

AB - Aims The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8±400.2, mean±SD) with unequal variances (p<0.001) and the butterfly marker showed the smallest mean artefact-volume (11.1±2.3 cm3) with a significant difference between markers (p=0.049). Conclusion Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.

KW - Magnetic technique

KW - magnetic markers

KW - lesion localization

KW - magnetometer

KW - porcine model

U2 - 10.1016/j.jmmm.2018.01.030

DO - 10.1016/j.jmmm.2018.01.030

M3 - Article

SN - 0304-8853

JO - JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

JF - JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

ER -