Feasibility study of tumor size classification via contrast-enhanced UWB breast imaging: A complex-domain analysis

TY - CHAP

T1 - Feasibility study of tumor size classification via contrast-enhanced UWB breast imaging

T2 - General Assembly and Scientific Symposium, 2011 XXXth URSI

AU - Ahmad, S. W.

AU - Chen, Y.

AU - Kosmas, P.

AU - Woo, W.L.

AU - Dlay, S.S.

PY - 2011/8

Y1 - 2011/8

N2 - Lesion classification using the tumor's backscatter signature can be very challenging in microwave breast imaging due to the small intrinsic contrast between the dielectric properties of dysplastic and normal tissues. A possible solution to this problem is to use microwave contrast agents such as microbubbles, where the differential breast response before and after the administration of the agent to a dysplastic inclusion is used to classify various anomaly properties (size, depth, morphology, etc.). In this paper, we study the feasibility of contrast-agent-aided imaging for lesion size classification by studying received signals in the complex domain. A finite-difference time-domain (FDTD) numerical phantom is employed to simulate electromagnetic (EM) wave propagation inside the breast and extract the reflected waveforms with and without microbubbles in the tumor site. The complex-domain transfer function of differential response is then used to draw the poles-zero plots (PZPs) and Bode plots (BPs), which demonstrate the viability of the proposed method for lesion size categorization.

AB - Lesion classification using the tumor's backscatter signature can be very challenging in microwave breast imaging due to the small intrinsic contrast between the dielectric properties of dysplastic and normal tissues. A possible solution to this problem is to use microwave contrast agents such as microbubbles, where the differential breast response before and after the administration of the agent to a dysplastic inclusion is used to classify various anomaly properties (size, depth, morphology, etc.). In this paper, we study the feasibility of contrast-agent-aided imaging for lesion size classification by studying received signals in the complex domain. A finite-difference time-domain (FDTD) numerical phantom is employed to simulate electromagnetic (EM) wave propagation inside the breast and extract the reflected waveforms with and without microbubbles in the tumor site. The complex-domain transfer function of differential response is then used to draw the poles-zero plots (PZPs) and Bode plots (BPs), which demonstrate the viability of the proposed method for lesion size categorization.

KW - biological organs

KW - biological tissues

KW - cellular biophysics

KW - electromagnetic wave propagation

KW - finite difference time-domain analysis

KW - gynaecology

KW - image classification

KW - medical image processing

KW - microwave imaging

KW - phantoms

KW - transfer functions

KW - tumours

KW - FDTD numerical phantom

KW - bode plots

KW - complex domain

KW - complex-domain analysis

KW - complex-domain transfer function

KW - contrast-agent-aided imaging

KW - contrast-enhanced UWB breast imaging

KW - dielectric properties

KW - dysplastic inclusion

KW - dysplastic tissues

KW - finite-difference time-domain numerical phantom

KW - lesion size categorization

KW - lesion size classification

KW - microbubbles

KW - microwave breast imaging

KW - microwave contrast agents

KW - poles-zero plots

KW - tumor size classification

KW - tumors backscatter signature

KW - Breast

KW - Dielectrics

KW - Lesions

KW - Microwave imaging

KW - Microwave theory and techniques

U2 - 10.1109/URSIGASS.2011.6051374

DO - 10.1109/URSIGASS.2011.6051374

M3 - Conference paper

SN - 978-1-4244-5117-3

SP - 1

EP - 4

BT - General Assembly and Scientific Symposium, 2011 XXXth URSI

PB - IEEE

Y2 - 13 August 2011 through 20 August 2011

ER -