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Fetal Speckle-Tracking: Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain

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Fetal Speckle-Tracking : Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain. / Semmler, Janina; Day, Thomas G.; Georgiopoulos, Georgios; Garcia-Gonzalez, Coral; Aguilera, Jesica; Vigneswaran, Trisha V.; Zidere, Vita; Miller, Owen I.; Sharland, Gurleen; Charakida, Marietta; Simpson, John M.

In: Journal of The American Society of Echocardiography, Vol. 33, No. 9, 09.2020, p. 1141-1146.e2.

Research output: Contribution to journalArticle

Harvard

Semmler, J, Day, TG, Georgiopoulos, G, Garcia-Gonzalez, C, Aguilera, J, Vigneswaran, TV, Zidere, V, Miller, OI, Sharland, G, Charakida, M & Simpson, JM 2020, 'Fetal Speckle-Tracking: Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain', Journal of The American Society of Echocardiography, vol. 33, no. 9, pp. 1141-1146.e2. https://doi.org/10.1016/j.echo.2020.03.013

APA

Semmler, J., Day, T. G., Georgiopoulos, G., Garcia-Gonzalez, C., Aguilera, J., Vigneswaran, T. V., Zidere, V., Miller, O. I., Sharland, G., Charakida, M., & Simpson, J. M. (2020). Fetal Speckle-Tracking: Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain. Journal of The American Society of Echocardiography, 33(9), 1141-1146.e2. https://doi.org/10.1016/j.echo.2020.03.013

Vancouver

Semmler J, Day TG, Georgiopoulos G, Garcia-Gonzalez C, Aguilera J, Vigneswaran TV et al. Fetal Speckle-Tracking: Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain. Journal of The American Society of Echocardiography. 2020 Sep;33(9):1141-1146.e2. https://doi.org/10.1016/j.echo.2020.03.013

Author

Semmler, Janina ; Day, Thomas G. ; Georgiopoulos, Georgios ; Garcia-Gonzalez, Coral ; Aguilera, Jesica ; Vigneswaran, Trisha V. ; Zidere, Vita ; Miller, Owen I. ; Sharland, Gurleen ; Charakida, Marietta ; Simpson, John M. / Fetal Speckle-Tracking : Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain. In: Journal of The American Society of Echocardiography. 2020 ; Vol. 33, No. 9. pp. 1141-1146.e2.

Bibtex Download

@article{782b329a697448348062e6e5834a5898,
title = "Fetal Speckle-Tracking: Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain",
abstract = "Background: There is a growing body of research on fetal speckle-tracking echocardiography because it is considered to be an angle-independent modality. The primary aim of this study was to investigate whether angle of insonation and acquisition frame rate (FR) influence left ventricular endocardial global longitudinal peak strain (GLS) in the fetus. Methods: Four-chamber views of 122 healthy fetuses were studied at three different angles of insonation (apex up/down, apex oblique, and apex perpendicular) at high and low acoustic FRs. GLS was calculated, and a linear mixed-model analysis was used for analysis. Six hundred fifty-six fetal echocardiographic clips were analyzed (288 in the second trimester, at a median gestation of 21 weeks [interquartile range (IQR), 1 week], and 368 in the third trimester, at a median gestation of 36 weeks [IQR, 2 weeks]). Results: Angle of insonation and FRs were significant determinants of GLS. Ventricular septum perpendicular to the ultrasound beam was associated with higher (more negative) GLS compared with apex up/down (at high FR: −21.8% vs −19.7%, P < .001; at low FR: −24.1% vs −21.4%, P < .001). Higher frames per second (FPS; median 149 FPS [IQR, 33 FPS] = 61 frames per cycle [FPC] [IQR, 17 FPC]) compared with lower FPS (median 51 FPS [IQR, 15 FPS] = 22 FPC [IQR, 7 FPC]) at the same insonation angle resulted in lower GLS (apex up/down: −19.7% vs −21.4%, P < .001; apex oblique: −21.2% vs −22.7%, P < .001; apex perpendicular: −21.8% vs −24.1%, P < .001). Conclusions: The present findings show that insonation angle and FR influence GLS significantly. These factors need to be considered when comparing studies with different acquisition protocols, when establishing normative values, and when interpreting pathology. Speckle-tracking echocardiography cannot be considered an angle-independent modality during fetal life.",
keywords = "2D strain, Angle of insonation, Fetal speckle-tracking, Fetus, Frame rate",
author = "Janina Semmler and Day, {Thomas G.} and Georgios Georgiopoulos and Coral Garcia-Gonzalez and Jesica Aguilera and Vigneswaran, {Trisha V.} and Vita Zidere and Miller, {Owen I.} and Gurleen Sharland and Marietta Charakida and Simpson, {John M.}",
year = "2020",
month = sep,
doi = "10.1016/j.echo.2020.03.013",
language = "English",
volume = "33",
pages = "1141--1146.e2",
journal = "Journal of The American Society of Echocardiography",
issn = "0894-7317",
publisher = "Mosby Inc.",
number = "9",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Fetal Speckle-Tracking

T2 - Impact of Angle of Insonation and Frame Rate on Global Longitudinal Strain

AU - Semmler, Janina

AU - Day, Thomas G.

AU - Georgiopoulos, Georgios

AU - Garcia-Gonzalez, Coral

AU - Aguilera, Jesica

AU - Vigneswaran, Trisha V.

AU - Zidere, Vita

AU - Miller, Owen I.

AU - Sharland, Gurleen

AU - Charakida, Marietta

AU - Simpson, John M.

PY - 2020/9

Y1 - 2020/9

N2 - Background: There is a growing body of research on fetal speckle-tracking echocardiography because it is considered to be an angle-independent modality. The primary aim of this study was to investigate whether angle of insonation and acquisition frame rate (FR) influence left ventricular endocardial global longitudinal peak strain (GLS) in the fetus. Methods: Four-chamber views of 122 healthy fetuses were studied at three different angles of insonation (apex up/down, apex oblique, and apex perpendicular) at high and low acoustic FRs. GLS was calculated, and a linear mixed-model analysis was used for analysis. Six hundred fifty-six fetal echocardiographic clips were analyzed (288 in the second trimester, at a median gestation of 21 weeks [interquartile range (IQR), 1 week], and 368 in the third trimester, at a median gestation of 36 weeks [IQR, 2 weeks]). Results: Angle of insonation and FRs were significant determinants of GLS. Ventricular septum perpendicular to the ultrasound beam was associated with higher (more negative) GLS compared with apex up/down (at high FR: −21.8% vs −19.7%, P < .001; at low FR: −24.1% vs −21.4%, P < .001). Higher frames per second (FPS; median 149 FPS [IQR, 33 FPS] = 61 frames per cycle [FPC] [IQR, 17 FPC]) compared with lower FPS (median 51 FPS [IQR, 15 FPS] = 22 FPC [IQR, 7 FPC]) at the same insonation angle resulted in lower GLS (apex up/down: −19.7% vs −21.4%, P < .001; apex oblique: −21.2% vs −22.7%, P < .001; apex perpendicular: −21.8% vs −24.1%, P < .001). Conclusions: The present findings show that insonation angle and FR influence GLS significantly. These factors need to be considered when comparing studies with different acquisition protocols, when establishing normative values, and when interpreting pathology. Speckle-tracking echocardiography cannot be considered an angle-independent modality during fetal life.

AB - Background: There is a growing body of research on fetal speckle-tracking echocardiography because it is considered to be an angle-independent modality. The primary aim of this study was to investigate whether angle of insonation and acquisition frame rate (FR) influence left ventricular endocardial global longitudinal peak strain (GLS) in the fetus. Methods: Four-chamber views of 122 healthy fetuses were studied at three different angles of insonation (apex up/down, apex oblique, and apex perpendicular) at high and low acoustic FRs. GLS was calculated, and a linear mixed-model analysis was used for analysis. Six hundred fifty-six fetal echocardiographic clips were analyzed (288 in the second trimester, at a median gestation of 21 weeks [interquartile range (IQR), 1 week], and 368 in the third trimester, at a median gestation of 36 weeks [IQR, 2 weeks]). Results: Angle of insonation and FRs were significant determinants of GLS. Ventricular septum perpendicular to the ultrasound beam was associated with higher (more negative) GLS compared with apex up/down (at high FR: −21.8% vs −19.7%, P < .001; at low FR: −24.1% vs −21.4%, P < .001). Higher frames per second (FPS; median 149 FPS [IQR, 33 FPS] = 61 frames per cycle [FPC] [IQR, 17 FPC]) compared with lower FPS (median 51 FPS [IQR, 15 FPS] = 22 FPC [IQR, 7 FPC]) at the same insonation angle resulted in lower GLS (apex up/down: −19.7% vs −21.4%, P < .001; apex oblique: −21.2% vs −22.7%, P < .001; apex perpendicular: −21.8% vs −24.1%, P < .001). Conclusions: The present findings show that insonation angle and FR influence GLS significantly. These factors need to be considered when comparing studies with different acquisition protocols, when establishing normative values, and when interpreting pathology. Speckle-tracking echocardiography cannot be considered an angle-independent modality during fetal life.

KW - 2D strain

KW - Angle of insonation

KW - Fetal speckle-tracking

KW - Fetus

KW - Frame rate

UR - http://www.scopus.com/inward/record.url?scp=85084548158&partnerID=8YFLogxK

U2 - 10.1016/j.echo.2020.03.013

DO - 10.1016/j.echo.2020.03.013

M3 - Article

AN - SCOPUS:85084548158

VL - 33

SP - 1141-1146.e2

JO - Journal of The American Society of Echocardiography

JF - Journal of The American Society of Echocardiography

SN - 0894-7317

IS - 9

ER -

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