Fiber optic photoacoustic probe with ultrasonic tracking for guiding minimally invasive procedures

TY - CHAP

T1 - Fiber optic photoacoustic probe with ultrasonic tracking for guiding minimally invasive procedures

AU - Xia, Wenfeng

AU - Mosse, Charles A.

AU - Colchester, Richard J.

AU - Mari, Jean Martial

AU - Nikitichev, Daniil I.

AU - West, Simeon J.

AU - Ourselin, Sebastien

AU - Beard, Paul C.

AU - Desjardins, Adrien E.

PY - 2014/7/21

Y1 - 2014/7/21

N2 - In a wide range of clinical procedures, accurate placement of medical devices such as needles and catheters is critical to optimize patient outcomes. Ultrasound imaging is often used to guide minimally invasive procedures, as it can provide real-time visualization of patient anatomy and medical devices. However, this modality can provide low image contrast for soft tissues, and poor visualization of medical devices that are steeply angled with respect to the incoming ultrasound beams. Photoacoustic sensors can provide information about the spatial distributions of tissue chromophores that could be valuable for guiding minimally invasive procedures. In this study, a system for guiding minimally invasive procedures using photoacoustic sensing was developed. This system included a miniature photoacoustic probe with three optical fibers: one with a bare end for photoacoustic excitation of tissue, a second for photoacoustic excitation of an optically absorbing coating at the distal end to transmit ultrasound, and a third with a Fabry-Pérot cavity at the distal end for receiving ultrasound. The position of the photoacoustic probe was determined with ultrasonic tracking, which involved transmitting pulses from a linear-array ultrasound imaging probe at the tissue surface, and receiving them with the fiber-optic ultrasound receiver in the photoacoustic probe. The axial resolution of photoacoustic sensing was better than 70 μm, and the tracking accuracy was better than 1 mm in both axial and lateral dimensions. By translating the photoacoustic probe, depth scans were obtained from different spatial positions, and two-dimensional images were reconstructed using a frequency-domain algorithm.

AB - In a wide range of clinical procedures, accurate placement of medical devices such as needles and catheters is critical to optimize patient outcomes. Ultrasound imaging is often used to guide minimally invasive procedures, as it can provide real-time visualization of patient anatomy and medical devices. However, this modality can provide low image contrast for soft tissues, and poor visualization of medical devices that are steeply angled with respect to the incoming ultrasound beams. Photoacoustic sensors can provide information about the spatial distributions of tissue chromophores that could be valuable for guiding minimally invasive procedures. In this study, a system for guiding minimally invasive procedures using photoacoustic sensing was developed. This system included a miniature photoacoustic probe with three optical fibers: one with a bare end for photoacoustic excitation of tissue, a second for photoacoustic excitation of an optically absorbing coating at the distal end to transmit ultrasound, and a third with a Fabry-Pérot cavity at the distal end for receiving ultrasound. The position of the photoacoustic probe was determined with ultrasonic tracking, which involved transmitting pulses from a linear-array ultrasound imaging probe at the tissue surface, and receiving them with the fiber-optic ultrasound receiver in the photoacoustic probe. The axial resolution of photoacoustic sensing was better than 70 μm, and the tracking accuracy was better than 1 mm in both axial and lateral dimensions. By translating the photoacoustic probe, depth scans were obtained from different spatial positions, and two-dimensional images were reconstructed using a frequency-domain algorithm.

KW - Fiber optic

KW - Minimally invasive procedures

KW - Photoacoustic imaging

KW - Ultrasonic tracking

KW - Ultrasound imaging

UR - http://www.scopus.com/inward/record.url?scp=85019521758&partnerID=8YFLogxK

U2 - 10.1117/12.2182647

DO - 10.1117/12.2182647

M3 - Conference paper

AN - SCOPUS:85019521758

SN - 9781628417012

VL - 9539

BT - European Conference on Biomedical Optics, ECBO 2015

PB - OSA - The Optical Society

T2 - European Conference on Biomedical Optics, ECBO 2015

Y2 - 21 June 2015 through 25 June 2015

ER -