Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

Barrie J. Marsh; Lauren Hampton; Sean Goggins; Christopher G. Frost

doi:10.1039/c4nj01050g

Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

Barrie J. Marsh, Lauren Hampton, Sean Goggins, Christopher G. Frost^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Electron-withdrawing or -donating groups are known to directly affect the Fe(iii/ii) formal potential of ferrocene derivatives by affecting their energy levels relative to the vacuum level. However, perhaps surprisingly, also more subtle indirect "tuning" of the formal potential is possible by changing the "dielectric environment". This is demonstrated here by systematically changing the chain length of alkyl-chain derivatives. The resulting formal potentials are shown to be correlated to the hydrophobicity of the ferrocene molecule which can be used to predict the redox potential of a ferrocene. This journal is

Original language	English
Pages (from-to)	5260-5263
Number of pages	4
Journal	NEW JOURNAL OF CHEMISTRY
Volume	38
Issue number	11
DOIs	https://doi.org/10.1039/c4nj01050g
Publication status	Published - 1 Nov 2014

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Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

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