Fritless Xterra Particles Encapsulated Within a Poly(butylmethacrylate) Based Monolith for Use in CEC

Aree Choodum, Panote Thavarungkul, Proespichaya Kanatharana, Norman William Smith

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Fritless columns were fabricated by encapsulating packing material within monolith for capillary electrochromatography. They were applied for separation of 3,4-methylenedioxymethamphetamine and metabolites. The packing material was suspended in polymerisation mixture and then forced into a pre-treated capillary following by polymerisation. This made the preparation much easier, saved time, cost and showed less tendency towards bubble formation with better resolution than with packed column. Using this fritless column, migration time of all analytes increased with buffer concentration and amount of organic component in mobile phase, but decreased on increasing the pH from 3.0 to 4.5 and then increased above pH 4.5.
Original languageEnglish
Pages (from-to)481 - 488
Number of pages8
JournalCHROMATOGRAPHIA
Volume69
Issue number5-6
DOIs
Publication statusPublished - Mar 2009

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