TY - JOUR
T1 - Gender, age and geographical representation over the past 50 years of schizophrenia research
AU - ANDES Network
AU - Alliende, Luz María
AU - Czepielewski, Leticia S.
AU - Aceituno, David
AU - Castañeda, Carmen Paz
AU - Diaz, Camila
AU - Iruretagoyena, Barbara
AU - Mena, Carlos
AU - Mena, Cristian
AU - Ramirez-Mahaluf, Juan Pablo
AU - Tepper, Ángeles
AU - Vasquez, Javiera
AU - Fonseca, Lais
AU - Machado, Viviane
AU - Hernández, Camilo E.
AU - Vargas-Upegui, Cristian
AU - Gomez-Cruz, Gladys
AU - Kobayashi-Romero, Luis F.
AU - Moncada-Habib, Tomas
AU - Evans-Lacko, Sara
AU - Bressan, Rodrigo
AU - Gama, Clarissa S.
AU - Lopez-Jaramillo, Carlos
AU - de la Fuente-Sandoval, Camilo
AU - Gonzalez-Valderrama, Alfonso
AU - Undurraga, Juan
AU - Gadelha, Ary
AU - Crossley, Nicolas A.
N1 - Funding Information:
Camilo de la Fuente-Sandoval was supported by Consejo Nacional de Ciencia y Tecnología - Sistema Nacional de Investigadores, Mexico, (CONACyT - SNI); and National Institutes of Health Grant Nos. R21 MH117434 and R01 MH110270. Nicolas Crossley and Juan Undurraga were supported by ANID-PIA-ACT192064, ANID-FONDECYT 1180358, 1200601. Juan Pablo Ramirez-Mahaluf was supported by ANID-FONDECYT post doctorate funding 3190311.
Funding Information:
This collaboration was made possible thanks to the Programa Iberoamericano de Ciencia y Tecnolog?a para el Desarrollo CYTED Redes to ANDES (218RT0547). Camilo de la Fuente-Sandoval was supported by Consejo Nacional de Ciencia y Tecnolog?a - Sistema Nacional de Investigadores, Mexico, (CONACyT - SNI); and National Institutes of Health Grant Nos. R21 MH117434 and R01 MH110270. Nicolas Crossley and Juan Undurraga were supported by ANID-PIA-ACT192064, ANID-FONDECYT 1180358, 1200601. Juan Pablo Ramirez-Mahaluf was supported by ANID-FONDECYT post doctorate funding 3190311.
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2022/1
Y1 - 2022/1
N2 - Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.
AB - Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.
KW - Age
KW - Diversity
KW - Gender
KW - Global diversity
KW - High-income countries
KW - Low-and-middle-income countries
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85120362323&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2021.114279
DO - 10.1016/j.psychres.2021.114279
M3 - Article
AN - SCOPUS:85120362323
SN - 0165-1781
VL - 307
JO - Psychiatry Research
JF - Psychiatry Research
M1 - 114279
ER -