Gender, age and geographical representation over the past 50 years of schizophrenia research

Luz María Alliende; Leticia S Czepielewski; David Aceituno; Carmen Paz Castañeda; Camila Diaz; Barbara Iruretagoyena; Carlos Mena; Cristian Mena; Juan Pablo Ramirez-Mahaluf; Ángeles Tepper; Javiera Vasquez; Lais Fonseca; Viviane Machado; Camilo E Hernández; Cristian Vargas-Upegui; Gladys Gomez-Cruz; Luis F Kobayashi-Romero; Tomas Moncada-Habib; Sara Evans-Lacko; Rodrigo Bressan; Clarissa S Gama; Carlos Lopez-Jaramillo; Camilo de la Fuente-Sandoval; Alfonso Gonzalez-Valderrama; Juan Undurraga; Ary Gadelha; Nicolas A Crossley; ANDES Network

doi:10.1016/j.psychres.2021.114279

Gender, age and geographical representation over the past 50 years of schizophrenia research

Luz María Alliende, Leticia S Czepielewski, David Aceituno, Carmen Paz Castañeda, Camila Diaz, Barbara Iruretagoyena, Carlos Mena, Cristian Mena, Juan Pablo Ramirez-Mahaluf, Ángeles Tepper, Javiera Vasquez, Lais Fonseca, Viviane Machado, Camilo E Hernández, Cristian Vargas-Upegui, Gladys Gomez-Cruz, Luis F Kobayashi-Romero, Tomas Moncada-Habib, Sara Evans-Lacko, Rodrigo BressanClarissa S Gama, Carlos Lopez-Jaramillo, Camilo de la Fuente-Sandoval, Alfonso Gonzalez-Valderrama, Juan Undurraga, Ary Gadelha, Nicolas A Crossley, ANDES Network

Research output: Contribution to journal › Article › peer-review

Abstract

Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.

Original language	English
Journal	Psychiatry Research
Volume	307
DOIs	https://doi.org/10.1016/j.psychres.2021.114279
Publication status	Published - 1 Jan 2022

Keywords

Age
Diversity
Gender
Global diversity
High-income countries
Low-and-middle-income countries
Schizophrenia
# Read it
5. Publications

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10.1016/j.psychres.2021.114279

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Alliende, L. M., Czepielewski, L. S., Aceituno, D., Castañeda, C. P., Diaz, C., Iruretagoyena, B., Mena, C., Mena, C., Ramirez-Mahaluf, J. P., Tepper, Á., Vasquez, J., Fonseca, L., Machado, V., Hernández, C. E., Vargas-Upegui, C., Gomez-Cruz, G., Kobayashi-Romero, L. F., Moncada-Habib, T., Evans-Lacko, S., ... Network, ANDES. (2022). Gender, age and geographical representation over the past 50 years of schizophrenia research. Psychiatry Research, 307. https://doi.org/10.1016/j.psychres.2021.114279

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title = "Gender, age and geographical representation over the past 50 years of schizophrenia research",

abstract = "Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.",

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Alliende, LM, Czepielewski, LS, Aceituno, D, Castañeda, CP, Diaz, C, Iruretagoyena, B, Mena, C, Mena, C, Ramirez-Mahaluf, JP, Tepper, Á, Vasquez, J, Fonseca, L, Machado, V, Hernández, CE, Vargas-Upegui, C, Gomez-Cruz, G, Kobayashi-Romero, LF, Moncada-Habib, T, Evans-Lacko, S , Bressan, R, Gama, CS, Lopez-Jaramillo, C, de la Fuente-Sandoval, C, Gonzalez-Valderrama, A, Undurraga, J, Gadelha, A, Crossley, NA & Network, ANDES 2022, 'Gender, age and geographical representation over the past 50 years of schizophrenia research', Psychiatry Research, vol. 307. https://doi.org/10.1016/j.psychres.2021.114279

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AU - Alliende, Luz María

AU - Czepielewski, Leticia S

AU - Aceituno, David

AU - Castañeda, Carmen Paz

AU - Diaz, Camila

AU - Iruretagoyena, Barbara

AU - Mena, Carlos

AU - Mena, Cristian

AU - Ramirez-Mahaluf, Juan Pablo

AU - Tepper, Ángeles

AU - Vasquez, Javiera

AU - Fonseca, Lais

AU - Machado, Viviane

AU - Hernández, Camilo E

AU - Vargas-Upegui, Cristian

AU - Gomez-Cruz, Gladys

AU - Kobayashi-Romero, Luis F

AU - Moncada-Habib, Tomas

AU - Evans-Lacko, Sara

AU - Bressan, Rodrigo

AU - Gama, Clarissa S

AU - Lopez-Jaramillo, Carlos

AU - de la Fuente-Sandoval, Camilo

AU - Gonzalez-Valderrama, Alfonso

AU - Undurraga, Juan

AU - Gadelha, Ary

AU - Crossley, Nicolas A

AU - Network, ANDES

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.

AB - Previous studies have suggested that subjects participating in schizophrenia research are not representative of the demographics of the global population of people with schizophrenia, particularly in terms of gender and geographical location. We here explored if this has evolved throughout the decades, examining changes in geographical location, gender and age of participants in studies of schizophrenia published in the last 50 years. We examined this using a meta-analytical approach on an existing database including over 3,000 studies collated for another project. We found that the proportion of studies and participants from low-and-middle income countries has significantly increased over time, with considerable input from studies from China. However, it is still low when compared to the global population they represent. Women have been historically under-represented in studies, and still are in high-income countries. However, a significantly higher proportion of female participants have been included in studies over time. The age of participants included has not changed significantly over time. Overall, there have been improvements in the geographical and gender representation of people with schizophrenia. However, there is still a long way to go so research can be representative of the global population of people with schizophrenia, particularly in geographical terms.

KW - Age

KW - Diversity

KW - Gender

KW - Global diversity

KW - High-income countries

KW - Low-and-middle-income countries

KW - Schizophrenia

KW - # Read it

KW - 5. Publications

U2 - 10.1016/j.psychres.2021.114279

DO - 10.1016/j.psychres.2021.114279

M3 - Article

SN - 0165-1781

VL - 307

JO - Psychiatry Research

JF - Psychiatry Research

ER -

Gender, age and geographical representation over the past 50 years of schizophrenia research

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Keywords

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