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Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene

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Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene. / Jacquet, Laureen; Hewitson, Heema; Wood, Victoria; Kadeva, Neli; Cornwell, Glenda; Codognotto, Stefano; Hobbs, Carl; Stephenson, Emma; Ilic, Dusko.

In: Stem Cell Research, Vol. 16, No. 2, 03.2016, p. 264-267.

Research output: Contribution to journalArticle

Harvard

Jacquet, L, Hewitson, H, Wood, V, Kadeva, N, Cornwell, G, Codognotto, S, Hobbs, C, Stephenson, E & Ilic, D 2016, 'Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene', Stem Cell Research, vol. 16, no. 2, pp. 264-267. https://doi.org/10.1016/j.scr.2016.01.012

APA

Jacquet, L., Hewitson, H., Wood, V., Kadeva, N., Cornwell, G., Codognotto, S., Hobbs, C., Stephenson, E., & Ilic, D. (2016). Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene. Stem Cell Research, 16(2), 264-267. https://doi.org/10.1016/j.scr.2016.01.012

Vancouver

Jacquet L, Hewitson H, Wood V, Kadeva N, Cornwell G, Codognotto S et al. Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene. Stem Cell Research. 2016 Mar;16(2):264-267. https://doi.org/10.1016/j.scr.2016.01.012

Author

Jacquet, Laureen ; Hewitson, Heema ; Wood, Victoria ; Kadeva, Neli ; Cornwell, Glenda ; Codognotto, Stefano ; Hobbs, Carl ; Stephenson, Emma ; Ilic, Dusko. / Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene. In: Stem Cell Research. 2016 ; Vol. 16, No. 2. pp. 264-267.

Bibtex Download

@article{bff7f17abc434b568535e5d183dab9e6,
title = "Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene",
abstract = "The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro and in vivo assays.",
author = "Laureen Jacquet and Heema Hewitson and Victoria Wood and Neli Kadeva and Glenda Cornwell and Stefano Codognotto and Carl Hobbs and Emma Stephenson and Dusko Ilic",
year = "2016",
month = mar,
doi = "10.1016/j.scr.2016.01.012",
language = "English",
volume = "16",
pages = "264--267",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "2",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene

AU - Jacquet, Laureen

AU - Hewitson, Heema

AU - Wood, Victoria

AU - Kadeva, Neli

AU - Cornwell, Glenda

AU - Codognotto, Stefano

AU - Hobbs, Carl

AU - Stephenson, Emma

AU - Ilic, Dusko

PY - 2016/3

Y1 - 2016/3

N2 - The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro and in vivo assays.

AB - The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal allele). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro and in vivo assays.

UR - http://www.scopus.com/inward/record.url?scp=84955574045&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2016.01.012

DO - 10.1016/j.scr.2016.01.012

M3 - Article

C2 - 27345979

VL - 16

SP - 264

EP - 267

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 2

ER -

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