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Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene

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Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene. / Miere, Cristian; Hewitson, Heema; Wood, Victoria; Kadeva, Neli; Cornwell, Glenda; Codognotto, Stefano; Stephenson, Emma; Ilic, Dusko.

In: Stem Cell Research, Vol. 16, No. 1, 01.2016, p. 189-191.

Research output: Contribution to journalArticle

Harvard

Miere, C, Hewitson, H, Wood, V, Kadeva, N, Cornwell, G, Codognotto, S, Stephenson, E & Ilic, D 2016, 'Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene', Stem Cell Research, vol. 16, no. 1, pp. 189-191. https://doi.org/10.1016/j.scr.2015.12.040

APA

Miere, C., Hewitson, H., Wood, V., Kadeva, N., Cornwell, G., Codognotto, S., Stephenson, E., & Ilic, D. (2016). Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene. Stem Cell Research, 16(1), 189-191. https://doi.org/10.1016/j.scr.2015.12.040

Vancouver

Miere C, Hewitson H, Wood V, Kadeva N, Cornwell G, Codognotto S et al. Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene. Stem Cell Research. 2016 Jan;16(1):189-191. https://doi.org/10.1016/j.scr.2015.12.040

Author

Miere, Cristian ; Hewitson, Heema ; Wood, Victoria ; Kadeva, Neli ; Cornwell, Glenda ; Codognotto, Stefano ; Stephenson, Emma ; Ilic, Dusko. / Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene. In: Stem Cell Research. 2016 ; Vol. 16, No. 1. pp. 189-191.

Bibtex Download

@article{a7be5c96adb043e393053825382c7505,
title = "Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene",
abstract = "The KCL029 human embryonic stem cell line was derived from an embryo donated for research that carried a c 814. T> C mutation in the WAS gene, which is linked to the Wiskott-Aldrich syndrome, a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia. The line is also carrier for a mutation p.N1152H in the gene encoding the cystic fibrosis transmembrane conductance regulator CFTR. The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro assays.",
author = "Cristian Miere and Heema Hewitson and Victoria Wood and Neli Kadeva and Glenda Cornwell and Stefano Codognotto and Emma Stephenson and Dusko Ilic",
year = "2016",
month = jan,
doi = "10.1016/j.scr.2015.12.040",
language = "English",
volume = "16",
pages = "189--191",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "1",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Generation of KCL029 research grade human embryonic stem cell line carrying a mutation in WAS gene

AU - Miere, Cristian

AU - Hewitson, Heema

AU - Wood, Victoria

AU - Kadeva, Neli

AU - Cornwell, Glenda

AU - Codognotto, Stefano

AU - Stephenson, Emma

AU - Ilic, Dusko

PY - 2016/1

Y1 - 2016/1

N2 - The KCL029 human embryonic stem cell line was derived from an embryo donated for research that carried a c 814. T> C mutation in the WAS gene, which is linked to the Wiskott-Aldrich syndrome, a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia. The line is also carrier for a mutation p.N1152H in the gene encoding the cystic fibrosis transmembrane conductance regulator CFTR. The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro assays.

AB - The KCL029 human embryonic stem cell line was derived from an embryo donated for research that carried a c 814. T> C mutation in the WAS gene, which is linked to the Wiskott-Aldrich syndrome, a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia. The line is also carrier for a mutation p.N1152H in the gene encoding the cystic fibrosis transmembrane conductance regulator CFTR. The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line propagation were performed in an animal product-free environment. Pluripotent state and differentiation potential were confirmed by in vitro assays.

UR - http://www.scopus.com/inward/record.url?scp=84954090582&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2015.12.040

DO - 10.1016/j.scr.2015.12.040

M3 - Article

C2 - 27345811

AN - SCOPUS:84954090582

VL - 16

SP - 189

EP - 191

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 1

ER -

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