Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models

Pablo Lamata de la Orden; Steven Niederer; Gernot Plank; Nic Smith

Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models

Pablo Lamata de la Orden, Steven Niederer, Gernot Plank, Nic Smith

Cardiovascular Imaging

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

6 Citations (Scopus)

Abstract

Model customisation to represent specific experimental or clinical cases is becoming increasingly important as simulations aim to characterise individual variability under physiological and pathological conditions. This study presents a new methodology to customise and regularise heart shape and fibres using imaging data (MRI and DT-MRI). The effect of using generic conductivity tensor values in electrophysiology simulations on these customised meshes is investigated. Simulation results demonstrate the ability of generic parameters to approximate epicardial activation patterns in healthy porcine hearts. Results also show a limited sensitivity of electrical activation times to the anisotropy of these parameters.

Original language	English
Title of host publication	STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART
Editors	O Camara, M Pop, K Rhode, M Sermesant, N Smith, A Young
Place of Publication	BERLIN
Publisher	Springer
Pages	252-260
Number of pages	9
Volume	6364 LNCS
ISBN (Print)	978-3-642-15834-6
Publication status	Published - 2010
Event	1st International Workshop on Statistical Atlases and Computational Models of the Heart - Bejing Duration: 20 Sept 2010 → …

Conference

Conference	1st International Workshop on Statistical Atlases and Computational Models of the Heart
City	Bejing
Period	20/09/2010 → …

Cite this

@inbook{1641dcbc886f47d8b7075717b437ad2e,

title = "Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models",

abstract = "Model customisation to represent specific experimental or clinical cases is becoming increasingly important as simulations aim to characterise individual variability under physiological and pathological conditions. This study presents a new methodology to customise and regularise heart shape and fibres using imaging data (MRI and DT-MRI). The effect of using generic conductivity tensor values in electrophysiology simulations on these customised meshes is investigated. Simulation results demonstrate the ability of generic parameters to approximate epicardial activation patterns in healthy porcine hearts. Results also show a limited sensitivity of electrical activation times to the anisotropy of these parameters.",

author = "{Lamata de la Orden}, Pablo and Steven Niederer and Gernot Plank and Nic Smith",

year = "2010",

language = "English",

isbn = "978-3-642-15834-6",

volume = "6364 LNCS",

pages = "252--260",

editor = "O Camara and M Pop and K Rhode and M Sermesant and N Smith and A Young",

booktitle = "STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART",

publisher = "Springer",

note = "1st International Workshop on Statistical Atlases and Computational Models of the Heart ; Conference date: 20-09-2010",

}

Lamata de la Orden, P, Niederer, S, Plank, G & Smith, N 2010, Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models. in O Camara, M Pop, K Rhode, M Sermesant, N Smith & A Young (eds), STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART. vol. 6364 LNCS, Springer, BERLIN, pp. 252-260, 1st International Workshop on Statistical Atlases and Computational Models of the Heart, Bejing, 20/09/2010.

Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models. / Lamata de la Orden, Pablo; Niederer, Steven; Plank, Gernot et al.
STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART. ed. / O Camara; M Pop; K Rhode; M Sermesant; N Smith; A Young. Vol. 6364 LNCS BERLIN: Springer, 2010. p. 252-260.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

TY - CHAP

T1 - Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models

AU - Lamata de la Orden, Pablo

AU - Niederer, Steven

AU - Plank, Gernot

AU - Smith, Nic

PY - 2010

Y1 - 2010

N2 - Model customisation to represent specific experimental or clinical cases is becoming increasingly important as simulations aim to characterise individual variability under physiological and pathological conditions. This study presents a new methodology to customise and regularise heart shape and fibres using imaging data (MRI and DT-MRI). The effect of using generic conductivity tensor values in electrophysiology simulations on these customised meshes is investigated. Simulation results demonstrate the ability of generic parameters to approximate epicardial activation patterns in healthy porcine hearts. Results also show a limited sensitivity of electrical activation times to the anisotropy of these parameters.

AB - Model customisation to represent specific experimental or clinical cases is becoming increasingly important as simulations aim to characterise individual variability under physiological and pathological conditions. This study presents a new methodology to customise and regularise heart shape and fibres using imaging data (MRI and DT-MRI). The effect of using generic conductivity tensor values in electrophysiology simulations on these customised meshes is investigated. Simulation results demonstrate the ability of generic parameters to approximate epicardial activation patterns in healthy porcine hearts. Results also show a limited sensitivity of electrical activation times to the anisotropy of these parameters.

M3 - Conference paper

SN - 978-3-642-15834-6

VL - 6364 LNCS

SP - 252

EP - 260

BT - STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART

A2 - Camara, O

A2 - Pop, M

A2 - Rhode, K

A2 - Sermesant, M

A2 - Smith, N

A2 - Young, A

PB - Springer

CY - BERLIN

T2 - 1st International Workshop on Statistical Atlases and Computational Models of the Heart

Y2 - 20 September 2010

ER -

Generic Conduction Parameters for Predicting Activation Waves in Customised Cardiac Electrophysiology Models

Abstract

Conference

Fingerprint

Cite this