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Genetic and Gene-Environment Influences on Disruptive Behavior Disorders

Research output: Chapter in Book/Report/Conference proceedingChapter

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Genetic and Gene-Environment Influences on Disruptive Behavior Disorders. / Barker, Edward D.; Cecil, Charlotte A. M.; Walton, Esther; Meehan, Alan J.

The Wiley Handbook of Disruptive and Impulse-Control Disorders. ed. / John E. Lochman; Walter Matthys. John Wiley & Sons, Ltd, 2017. p. 125-141.

Research output: Chapter in Book/Report/Conference proceedingChapter

Harvard

Barker, ED, Cecil, CAM, Walton, E & Meehan, AJ 2017, Genetic and Gene-Environment Influences on Disruptive Behavior Disorders. in JE Lochman & W Matthys (eds), The Wiley Handbook of Disruptive and Impulse-Control Disorders. John Wiley & Sons, Ltd, pp. 125-141. https://doi.org/10.1002/9781119092254.ch8

APA

Barker, E. D., Cecil, C. A. M., Walton, E., & Meehan, A. J. (2017). Genetic and Gene-Environment Influences on Disruptive Behavior Disorders. In J. E. Lochman, & W. Matthys (Eds.), The Wiley Handbook of Disruptive and Impulse-Control Disorders (pp. 125-141). John Wiley & Sons, Ltd. https://doi.org/10.1002/9781119092254.ch8

Vancouver

Barker ED, Cecil CAM, Walton E, Meehan AJ. Genetic and Gene-Environment Influences on Disruptive Behavior Disorders. In Lochman JE, Matthys W, editors, The Wiley Handbook of Disruptive and Impulse-Control Disorders. John Wiley & Sons, Ltd. 2017. p. 125-141 https://doi.org/10.1002/9781119092254.ch8

Author

Barker, Edward D. ; Cecil, Charlotte A. M. ; Walton, Esther ; Meehan, Alan J. / Genetic and Gene-Environment Influences on Disruptive Behavior Disorders. The Wiley Handbook of Disruptive and Impulse-Control Disorders. editor / John E. Lochman ; Walter Matthys. John Wiley & Sons, Ltd, 2017. pp. 125-141

Bibtex Download

@inbook{d12506c787dd4230b1908f907a9725af,
title = "Genetic and Gene-Environment Influences on Disruptive Behavior Disorders",
abstract = "This chapter first provides an overview of the influences on the manifestation of disruptive behavior disorders (DBDs) in children and adolescents, with a focus on conduct disorder (CD) and oppositional defiant disorder (ODD). Next, it reviews molecular genetic approaches—including candidate gene (hypothesis‐driven) and genome‐wide (hypothesis‐free) studies. The chapter further examines studies of gene‐environment (G×E) interplay. G×E interactions occur when an environmental influence on a trait or phenotype is dependent on an individual's genotype, or when an individual's genetic predispositions are expressed differently under distinct environmental conditions. Theoretical underpinnings of G×E have most often been articulated within the diathesis‐stress model, whereby genetic vulnerability (or diathesis) for phenotype is activated or exacerbated in the presence of certain environmental stressors. The chapter closes with a discussion on current challenges and proposes some key ways to move the area forward in the future.",
author = "Barker, {Edward D.} and Cecil, {Charlotte A. M.} and Esther Walton and Meehan, {Alan J.}",
year = "2017",
month = oct,
day = "30",
doi = "10.1002/9781119092254.ch8",
language = "English",
isbn = "9781119092162",
pages = "125--141",
editor = "Lochman, {John E.} and Walter Matthys",
booktitle = "The Wiley Handbook of Disruptive and Impulse-Control Disorders",
publisher = "John Wiley & Sons, Ltd",

}

RIS (suitable for import to EndNote) Download

TY - CHAP

T1 - Genetic and Gene-Environment Influences on Disruptive Behavior Disorders

AU - Barker, Edward D.

AU - Cecil, Charlotte A. M.

AU - Walton, Esther

AU - Meehan, Alan J.

PY - 2017/10/30

Y1 - 2017/10/30

N2 - This chapter first provides an overview of the influences on the manifestation of disruptive behavior disorders (DBDs) in children and adolescents, with a focus on conduct disorder (CD) and oppositional defiant disorder (ODD). Next, it reviews molecular genetic approaches—including candidate gene (hypothesis‐driven) and genome‐wide (hypothesis‐free) studies. The chapter further examines studies of gene‐environment (G×E) interplay. G×E interactions occur when an environmental influence on a trait or phenotype is dependent on an individual's genotype, or when an individual's genetic predispositions are expressed differently under distinct environmental conditions. Theoretical underpinnings of G×E have most often been articulated within the diathesis‐stress model, whereby genetic vulnerability (or diathesis) for phenotype is activated or exacerbated in the presence of certain environmental stressors. The chapter closes with a discussion on current challenges and proposes some key ways to move the area forward in the future.

AB - This chapter first provides an overview of the influences on the manifestation of disruptive behavior disorders (DBDs) in children and adolescents, with a focus on conduct disorder (CD) and oppositional defiant disorder (ODD). Next, it reviews molecular genetic approaches—including candidate gene (hypothesis‐driven) and genome‐wide (hypothesis‐free) studies. The chapter further examines studies of gene‐environment (G×E) interplay. G×E interactions occur when an environmental influence on a trait or phenotype is dependent on an individual's genotype, or when an individual's genetic predispositions are expressed differently under distinct environmental conditions. Theoretical underpinnings of G×E have most often been articulated within the diathesis‐stress model, whereby genetic vulnerability (or diathesis) for phenotype is activated or exacerbated in the presence of certain environmental stressors. The chapter closes with a discussion on current challenges and proposes some key ways to move the area forward in the future.

U2 - 10.1002/9781119092254.ch8

DO - 10.1002/9781119092254.ch8

M3 - Chapter

SN - 9781119092162

SP - 125

EP - 141

BT - The Wiley Handbook of Disruptive and Impulse-Control Disorders

A2 - Lochman, John E.

A2 - Matthys, Walter

PB - John Wiley & Sons, Ltd

ER -

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