Genetic and real-world clinical data, combined with empirical validation, nominate jak-stat signaling as a target for Alzheimer’s disease therapeutic development

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Transcription 100%
• JAK-STAT Signaling Pathway 100%
• Genome-Wide Association Study 100%
• JAK-STAT Signaling 100%
• Janus Kinase 1 100%
• RNA 66%
• Single-Nucleotide Polymorphism 33%
• Genetic Divergence 33%
• Genomics 33%
• Gene Expression 33%
• Genetic Association 33%
• Comorbidity 33%

Neuroscience

• Alzheimer's Disease 100%
• JAK-STAT Signaling Pathway 100%
• JAK-STAT Signaling 100%
• Genome-Wide Association Study 50%
• Janus Kinase 1 50%
• In Vivo 16%
• Comorbidity 16%
• Gene Expression 16%
• Single-Nucleotide Polymorphism 16%
• In Vitro 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Alzheimer's Disease 100%
• JAK-STAT Signaling 100%
• Diseases 50%
• Janus Kinase 1 50%
• Inflammation 16%
• Comorbidity 16%