Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci

W O C M Cookson, B Ubhi, R Lawrence, G R Abecasis, A J Walley, H E Cox, R Coleman, N I Leaves, R C Trembath, M F Moffatt, J I Harper

Research output: Contribution to journalArticlepeer-review

344 Citations (Scopus)

Abstract

We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity
Original languageEnglish
Pages (from-to)372 - 373
Number of pages2
JournalNature Genetics
Volume27
Issue number4
DOIs
Publication statusPublished - 2001

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