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Global prevalence of obsessive-compulsive and related disorders: a systematic review and modelling study: Global prevalence of obsessive-compulsive disorder

  • Yi Deun Jeong
  • , Dong Keon Yon*
  • , Samuele Cortese
  • , Paolo Fusar-Poli
  • , Marco Solmi
  • *Corresponding author for this work
  • Department of Family Medicine, Kyung Hee University Medical Center, Kyung Hee 12 University College of Medicine, Seoul, South Korea
  • Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea
  • KyungHee University College of Medicine
  • Kyung Hee University Hospital
  • Kyung Hee University
  • Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea
  • European Gravitational Observatory (EGO)
  • University of Southampton
  • Solent NHS Trust
  • University of Nottingham
  • Hassenfeld Children’s Hospital at NYU Langone
  • Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK
  • Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK
  • DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University of Bari "Aldo Moro", Bari, Italy
  • Section of Psychiatry, Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy
  • OASIS service, South London and Maudsley NHS Foundation Trust, London, United Kingdom
  • Early Psychosis: Interventions and Clinical-detection (EPIC) lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
  • Institute for Radiology, CCM
  • University of Ottawa
  • The Ottawa Hospital
  • Ottawa Hospital Research Institute
  • Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany
  • School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.

Research output: Contribution to journalReview articlepeer-review

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Abstract

Objective: Obsessive-compulsive disorder (OCD) is one of the common mental disorders globally. However, there are limited studies on the prevalence of OCD and four other disorders (hoarding disorder [HD], excoriation disorder [ED], body dysmorphic disorder [BDD], and trichotillomania) categorized under obsessive-compulsive and related disorders (OCRDs). Therefore, this study aimed to fill the epidemiological gap in the current literature.
Methods: We systematically searched PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Google Scholar from inception to June 8, 2025. Studies representative of national or subnational general populations, with diagnoses based on the Diagnostic and Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases, 10th edition (ICD‐10) criteria, were included. A Bayesian hierarchical linear mixed model was used to estimate the lifetime prevalence of OCD at the global, regional, and national levels, with estimates reported with 95% credible intervals. We examined the association between OCD prevalence and the Socio-demographic Index (SDI), and estimated age-specific point prevalence of OCD. This study was registered with PROSPERO (CRD420251070461).
Results: A total of 112 studies reporting OCRD prevalence rates were included. The global lifetime Bayesian prevalence of OCD across all ages was estimated at 2.57% according to ICD-10 criteria, 3.10% according to DSM-III, 2.28% according to DSM-IV, and 2.82% according to DSM-5. Lifetime prevalence of OCD was negatively correlated with the SDI, indicating lower prevalence estimates in countries with higher SDI. The age-specific prevalence of OCD increased sharply in the teenage years and peaked in the late 20s to early 30s. Point prevalence ranged across studies from 0.98% to 5.81% for HD, from 2.33% to 7.68% for ED, from 0.44% to 15.21% for BDD, and from 0.0% to 2.12% for trichotillomania.
Conclusions: This study estimated the global prevalence of OCD according to diagnostic criteria, underscoring the role of diagnostic definitions in shaping epidemiological understanding.
Original languageEnglish
JournalThe American Journal of Psychiatry
Publication statusAccepted/In press - 3 Jun 2026

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