King's College London

Research portal

Green tea effects on cognition, mood and human brain function: A systematic review

Research output: Contribution to journalArticlepeer-review

Edele Mancini, Christoph Beglinger, Jürgen Drewe, Davide Zanchi, Undine E. Lang, Stefan Borgwardt

Original languageEnglish
Early online date27 Jul 2017
Accepted/In press21 Jul 2017
E-pub ahead of print27 Jul 2017


King's Authors


Background: Green tea (Camellia sinensis) is a beverage consumed for thousands of years. Numerous claims about the benefits of its consumption were stated and investigated. As green tea is experiencing a surge in popularity in Western culture and as millions of people all over the world drink it every day, it is relevant to understand its effects on the human brain.

Purpose: To assess the current state of knowledge in the literature regarding the effects of green tea or green tea extracts, L-theanine and epigallocatechin gallate both components of green tea - on general neuropsychology, on the sub-category cognition and on brain functions in humans. Methods We systematically searched on PubMed database and selected studies by predefined eligibility criteria. We then assessed their quality and extracted data. We structured our effort according to the PRISMA statement.

Outcome: We reviewed and assessed 21 studies, 4 of which were randomised controlled trials, 12 cross-over studies (both assessed with an adapted version of the DELPHI-list), 4 were cross-sectional studies and one was a cohort study (both assessed with an adapted version of the Newcastle-Ottawa assessment scale). The average study quality as appraised by means of the DELPHI-list was good (8.06/9); the studies evaluated with the Newcastle-Ottawa-scale were also good (6.7/9).

Conclusions: The reviewed studies presented evidence that green tea influences psychopathological symptoms (e.g. reduction of anxiety), cognition (e.g. benefits in memory and attention) and brain function (e.g. activation of working memory seen in functional MRI). The effects of green tea cannot be attributed to a single constituent of the beverage. This is exemplified in the finding that beneficial green tea effects on cognition are observed under the combined influence of both caffeine and L-theanine, whereas separate administration of either substance was found to have a lesser impact.

Download statistics

No data available

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454