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Ground control to major tom: "prepare for HIV Landing"

Research output: Contribution to journalShort survey

Marina Lusic, Mauro Giacca

Original languageEnglish
Pages (from-to)557-559
Number of pages3
JournalCell Host and Microbe
Volume16
Issue number5
DOIs
Publication statusPublished - 12 Nov 2014

King's Authors

Abstract

Productive HIV-1 infection requires viral cDNA integration into the host genome, an event catalyzed by HIV-1 integrase. In this issue of Cell Host & Microbe, Demeulemeester et al. (2014) report the existence of natural integrase polymorphisms that retarget viral integration away from gene-dense regions and are associated with rapid disease progression.

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