Ground control to major tom: "prepare for HIV Landing"

TY - JOUR

T1 - Ground control to major tom

T2 - "prepare for HIV Landing"

AU - Lusic, Marina

AU - Giacca, Mauro

PY - 2014/11/12

Y1 - 2014/11/12

N2 - Productive HIV-1 infection requires viral cDNA integration into the host genome, an event catalyzed by HIV-1 integrase. In this issue of Cell Host & Microbe, Demeulemeester et al. (2014) report the existence of natural integrase polymorphisms that retarget viral integration away from gene-dense regions and are associated with rapid disease progression.

AB - Productive HIV-1 infection requires viral cDNA integration into the host genome, an event catalyzed by HIV-1 integrase. In this issue of Cell Host & Microbe, Demeulemeester et al. (2014) report the existence of natural integrase polymorphisms that retarget viral integration away from gene-dense regions and are associated with rapid disease progression.

UR - http://www.scopus.com/inward/record.url?scp=84910673504&partnerID=8YFLogxK

U2 - 10.1016/j.chom.2014.10.012

DO - 10.1016/j.chom.2014.10.012

M3 - Short survey

C2 - 25525787

AN - SCOPUS:84910673504

SN - 1931-3128

VL - 16

SP - 557

EP - 559

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 5

ER -