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Halogen Bonding Helicates Encompassing Iodonium Cations

Research output: Contribution to journalArticlepeer-review

Alan Vanderkooy, Arvind Kumar Gupta, Tamás Földes, Sofia Lindblad, Andreas Orthaber, Imre Pápai, Máté Erdélyi

Original languageEnglish
Pages (from-to)9012-9016
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number27
Early online date5 Jun 2019
E-pub ahead of print5 Jun 2019
Published5 Jul 2019

King's Authors


The first halonium-ion-based helices were designed and synthesized using oligo-aryl/pyridylene-ethynylene backbones that fold around reactive iodonium ions. Halogen bonding interactions stabilize the iodonium ions within the helices. Remarkably, the distance between two iodonium ions within a helix is shorter than the sum of their van der Waals radii. The helical conformations were characterized by X-ray crystallography in the solid state, by NMR spectroscopy in solution and corroborated by DFT calculations. The helical complexes possess potential synthetic utility, as demonstrated by their ability to induce iodocyclization of 4-penten-1-ol.

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