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Health and fertility in World Health Organization group 2 anovulatory women

Research output: Contribution to journalLiterature reviewpeer-review

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Health and fertility in World Health Organization group 2 anovulatory women. / Baird, D. T.; Balen, A.; Escobar-Morreale, H. F.; Evers, J. L. H.; Fauser, B. C. J. M.; Franks, S.; Glasier, A.; Homburg, R.; La Vecchia, C.; Crosignani, P. G.; Devroey, P.; Diedrich, K.; Fraser, L.; Gianaroli, L.; Liebaers, I.; Sunde, A.; Tapanainen, J. S.; Tarlatzis, B.; Van Steirteghem, A.; Veiga, A.; Evers, J. L. H.; ESHRE Capri Workshop Grp.

In: HUMAN REPRODUCTION UPDATE, Vol. 18, No. 5, dms019, 09.2012, p. 586-599.

Research output: Contribution to journalLiterature reviewpeer-review

Harvard

Baird, DT, Balen, A, Escobar-Morreale, HF, Evers, JLH, Fauser, BCJM, Franks, S, Glasier, A, Homburg, R, La Vecchia, C, Crosignani, PG, Devroey, P, Diedrich, K, Fraser, L, Gianaroli, L, Liebaers, I, Sunde, A, Tapanainen, JS, Tarlatzis, B, Van Steirteghem, A, Veiga, A, Evers, JLH & ESHRE Capri Workshop Grp 2012, 'Health and fertility in World Health Organization group 2 anovulatory women', HUMAN REPRODUCTION UPDATE, vol. 18, no. 5, dms019, pp. 586-599. https://doi.org/10.1093/humupd/dms019

APA

Baird, D. T., Balen, A., Escobar-Morreale, H. F., Evers, J. L. H., Fauser, B. C. J. M., Franks, S., Glasier, A., Homburg, R., La Vecchia, C., Crosignani, P. G., Devroey, P., Diedrich, K., Fraser, L., Gianaroli, L., Liebaers, I., Sunde, A., Tapanainen, J. S., Tarlatzis, B., Van Steirteghem, A., ... ESHRE Capri Workshop Grp (2012). Health and fertility in World Health Organization group 2 anovulatory women. HUMAN REPRODUCTION UPDATE, 18(5), 586-599. [dms019]. https://doi.org/10.1093/humupd/dms019

Vancouver

Baird DT, Balen A, Escobar-Morreale HF, Evers JLH, Fauser BCJM, Franks S et al. Health and fertility in World Health Organization group 2 anovulatory women. HUMAN REPRODUCTION UPDATE. 2012 Sep;18(5):586-599. dms019. https://doi.org/10.1093/humupd/dms019

Author

Baird, D. T. ; Balen, A. ; Escobar-Morreale, H. F. ; Evers, J. L. H. ; Fauser, B. C. J. M. ; Franks, S. ; Glasier, A. ; Homburg, R. ; La Vecchia, C. ; Crosignani, P. G. ; Devroey, P. ; Diedrich, K. ; Fraser, L. ; Gianaroli, L. ; Liebaers, I. ; Sunde, A. ; Tapanainen, J. S. ; Tarlatzis, B. ; Van Steirteghem, A. ; Veiga, A. ; Evers, J. L. H. ; ESHRE Capri Workshop Grp. / Health and fertility in World Health Organization group 2 anovulatory women. In: HUMAN REPRODUCTION UPDATE. 2012 ; Vol. 18, No. 5. pp. 586-599.

Bibtex Download

@article{3472a3c0a08248c9b333d61824fb4036,
title = "Health and fertility in World Health Organization group 2 anovulatory women",
abstract = "Disruption of ovulation occurs in different types of clinical infertility. The World Health Organization (WHO) has provided a classification of ovulation disorders. This review focuses on WHO group 2 anovulation.Searches were performed in Medline/PubMed and EMBASE. Each subject summary was presented to the European Society of Human Reproduction and Embryology (ESHRE) Workshop Group, where omissions or disagreements were resolved by discussion.Disorders resulting in ovulatory disturbances are a relatively common cause of infertility. They occur most frequently in the context of WHO group 2 anovulation as reflected, for example, in the polycystic ovary syndrome (PCOS). The aetiology of PCOS remains unclear but evidence exists for a multifactorial origin with a genetic predisposition. Women with PCOS show an increased time to pregnancy but their eventual family size is not necessarily reduced. Also their frequency of miscarriage does not appear increased. Clomiphene citrate is still the first-line treatment in subfertile anovulatory patients with PCOS, with gonadotrophins and laparoscopic ovarian surgery as second-line options. Aromatase inhibitors show promising results.Long-term health risks in patients with WHO group 2 anovulation demand their general health be monitored, even after their reproductive needs have been fulfilled. Metabolic and cardiovascular risk prevention in women with PCOS should start as early as possible. It is not easy to analyse the possible role of PCOS, independent of obesity, metabolic syndrome, insulin resistance and diabetes, on long-term health.",
author = "Baird, {D. T.} and A. Balen and Escobar-Morreale, {H. F.} and Evers, {J. L. H.} and Fauser, {B. C. J. M.} and S. Franks and A. Glasier and R. Homburg and {La Vecchia}, C. and Crosignani, {P. G.} and P. Devroey and K. Diedrich and L. Fraser and L. Gianaroli and I. Liebaers and A. Sunde and Tapanainen, {J. S.} and B. Tarlatzis and {Van Steirteghem}, A. and A. Veiga and Evers, {J. L. H.} and {ESHRE Capri Workshop Grp}",
year = "2012",
month = sep,
doi = "10.1093/humupd/dms019",
language = "English",
volume = "18",
pages = "586--599",
journal = "HUMAN REPRODUCTION UPDATE",
issn = "1355-4786",
publisher = "Oxford University Press",
number = "5",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Health and fertility in World Health Organization group 2 anovulatory women

AU - Baird, D. T.

AU - Balen, A.

AU - Escobar-Morreale, H. F.

AU - Evers, J. L. H.

AU - Fauser, B. C. J. M.

AU - Franks, S.

AU - Glasier, A.

AU - Homburg, R.

AU - La Vecchia, C.

AU - Crosignani, P. G.

AU - Devroey, P.

AU - Diedrich, K.

AU - Fraser, L.

AU - Gianaroli, L.

AU - Liebaers, I.

AU - Sunde, A.

AU - Tapanainen, J. S.

AU - Tarlatzis, B.

AU - Van Steirteghem, A.

AU - Veiga, A.

AU - Evers, J. L. H.

AU - ESHRE Capri Workshop Grp

PY - 2012/9

Y1 - 2012/9

N2 - Disruption of ovulation occurs in different types of clinical infertility. The World Health Organization (WHO) has provided a classification of ovulation disorders. This review focuses on WHO group 2 anovulation.Searches were performed in Medline/PubMed and EMBASE. Each subject summary was presented to the European Society of Human Reproduction and Embryology (ESHRE) Workshop Group, where omissions or disagreements were resolved by discussion.Disorders resulting in ovulatory disturbances are a relatively common cause of infertility. They occur most frequently in the context of WHO group 2 anovulation as reflected, for example, in the polycystic ovary syndrome (PCOS). The aetiology of PCOS remains unclear but evidence exists for a multifactorial origin with a genetic predisposition. Women with PCOS show an increased time to pregnancy but their eventual family size is not necessarily reduced. Also their frequency of miscarriage does not appear increased. Clomiphene citrate is still the first-line treatment in subfertile anovulatory patients with PCOS, with gonadotrophins and laparoscopic ovarian surgery as second-line options. Aromatase inhibitors show promising results.Long-term health risks in patients with WHO group 2 anovulation demand their general health be monitored, even after their reproductive needs have been fulfilled. Metabolic and cardiovascular risk prevention in women with PCOS should start as early as possible. It is not easy to analyse the possible role of PCOS, independent of obesity, metabolic syndrome, insulin resistance and diabetes, on long-term health.

AB - Disruption of ovulation occurs in different types of clinical infertility. The World Health Organization (WHO) has provided a classification of ovulation disorders. This review focuses on WHO group 2 anovulation.Searches were performed in Medline/PubMed and EMBASE. Each subject summary was presented to the European Society of Human Reproduction and Embryology (ESHRE) Workshop Group, where omissions or disagreements were resolved by discussion.Disorders resulting in ovulatory disturbances are a relatively common cause of infertility. They occur most frequently in the context of WHO group 2 anovulation as reflected, for example, in the polycystic ovary syndrome (PCOS). The aetiology of PCOS remains unclear but evidence exists for a multifactorial origin with a genetic predisposition. Women with PCOS show an increased time to pregnancy but their eventual family size is not necessarily reduced. Also their frequency of miscarriage does not appear increased. Clomiphene citrate is still the first-line treatment in subfertile anovulatory patients with PCOS, with gonadotrophins and laparoscopic ovarian surgery as second-line options. Aromatase inhibitors show promising results.Long-term health risks in patients with WHO group 2 anovulation demand their general health be monitored, even after their reproductive needs have been fulfilled. Metabolic and cardiovascular risk prevention in women with PCOS should start as early as possible. It is not easy to analyse the possible role of PCOS, independent of obesity, metabolic syndrome, insulin resistance and diabetes, on long-term health.

U2 - 10.1093/humupd/dms019

DO - 10.1093/humupd/dms019

M3 - Literature review

VL - 18

SP - 586

EP - 599

JO - HUMAN REPRODUCTION UPDATE

JF - HUMAN REPRODUCTION UPDATE

SN - 1355-4786

IS - 5

M1 - dms019

ER -

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