Higher cough flow is associated with lower risk of pneumonia in acute stroke

Stefan T. Kulnik*, Surinder S. Birring, John Hodsoll, John Moxham, Gerrard F. Rafferty, Lalit Kalra

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

There is little available evidence to demonstrate how cough strength mediates the risk of aspiration-related pneumonia in acute stroke. Our secondary analysis of trial data indicates that risk of pneumonia reduces with increasing peak cough flow (PCF) of voluntary cough (OR 0.994 for each 1 L/min increase in PCF, 95% CI 0.988 to 1.0, p=0.035); and to a lesser degree with increasing PCF of reflex cough (OR 0.998 for each 1 L/min increase in PCF, 95% CI 0.992 to 1.004, p=0.475). These data serve hypothesis generation. Further studies are needed to confirm these findings and validate their clinical utility.

Original languageEnglish
JournalThorax
Early online date1 Feb 2016
DOIs
Publication statusE-pub ahead of print - 1 Feb 2016

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