Highly undersampled phase-contrast flow measurements using compartment-based k-t principal component analysis

TY - JOUR

T1 - Highly undersampled phase-contrast flow measurements using compartment-based k-t principal component analysis

AU - Giese, Daniel

AU - Schaeffter, Tobias

AU - Kozerke, Sebastian

PY - 2013/2

Y1 - 2013/2

N2 - The applicability of cine blood flow measurements in a clinical setting is often compromised by the long scan times associated with phase-contrast imaging. In this work, we propose an extension to the kt principal component analysis method and demonstrate that by definition of spatial compartment-dependent temporal basis functions, significant improvements in reconstruction accuracy can be achieved relative to the original kt principal component analysis and kt SENSE formulations. Using this method, it is shown that prospective nominal undersampling of up to 16 corresponding to a net acceleration factor of 8 including training data acquisition can be realized while keeping the error in stroke volume below 5%. As a practical application, the acquisition of cine flow data in the aorta is demonstrated permitting assessment of two-dimensional velocity images and pulse wave velocities at 100 frames per second in a single breathhold per slice. 

AB - The applicability of cine blood flow measurements in a clinical setting is often compromised by the long scan times associated with phase-contrast imaging. In this work, we propose an extension to the kt principal component analysis method and demonstrate that by definition of spatial compartment-dependent temporal basis functions, significant improvements in reconstruction accuracy can be achieved relative to the original kt principal component analysis and kt SENSE formulations. Using this method, it is shown that prospective nominal undersampling of up to 16 corresponding to a net acceleration factor of 8 including training data acquisition can be realized while keeping the error in stroke volume below 5%. As a practical application, the acquisition of cine flow data in the aorta is demonstrated permitting assessment of two-dimensional velocity images and pulse wave velocities at 100 frames per second in a single breathhold per slice. 

KW - flow measurements

KW - phase contrast

KW - k-t acceleration

KW - constrained reconstruction

KW - principal component analysis

KW - MAGNETIC-RESONANCE

KW - BLAST RECONSTRUCTION

KW - DYNAMIC MRI

KW - SENSE

KW - GRAPPA

KW - ACCURACY

KW - QUANTIFICATION

U2 - 10.1002/mrm.24273

DO - 10.1002/mrm.24273

M3 - Article

SN - 0740-3194

VL - 69

SP - 434

EP - 443

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 2

M1 - N/A

ER -