Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission

Sean Halstead; Chloe X. Yap; Nicola Warren; Sri Mahavir Agarwal; Bodyl A. Brand; Sherry Kit Wa Chan; Andrea Cipriani; Christoph U. Correll; Nicolas Crossley; Enrico D'Ambrosio; Robin Emsley; Joseph Firth; Fiona Gaughran; Siobhan Gee; Margaret Hahn; Joseph F. Hayes; Adrian Heald; Oliver D. Howes; John M. Kane; Maria Kapi; Stefan Leucht; Nicholas Meyer; Brian O'Donoghue; Emmanuel Okeke; Benjamin I. Perry; Marco Solmi; Iris E. Sommer; Vivek Srivastava; Heidi Taipale; David Taylor; Jari Tiihonen; Allan H. Young; Najma Siddiqi; Dan Siskind; Simon Rosenbaum; Cherrie Galletly; Stephanie Allan; Constanza Caneo; Rebekah Carney; Andre F. Carvalho; Mary Lou Chatterton; Jackie Curtis; Erin Hoare; Sarah E. Jackson; Steve Kisely; Karina Lovell; Patrick D. McGorry; Cathrine Mihalopoulos; Toby Pillinger; Jerome Sarris; Felipe B. Schuch; David Shiers; Lee Smith; Shuichi Suetani; Johanna Taylor; Scott B. Teasdale; Graham Thornicroft; John Torous; Tim Usherwood; Davy Vancampfort; Nicola Veronese; Philip B. Ward; Alison R. Yung; Eóin Killackey; Brendon Stubbs; Robert A. McCutcheon

doi:10.1016/S2215-0366(25)00162-2

Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission

Sean Halstead^*
, Chloe X. Yap
, Nicola Warren
, Sri Mahavir Agarwal
, Bodyl A. Brand
, Sherry Kit Wa Chan
, Andrea Cipriani
, Christoph U. Correll
, Nicolas Crossley
, Enrico D'Ambrosio
, Robin Emsley
, Joseph Firth
, Fiona Gaughran
, Siobhan Gee
, Margaret Hahn
, Joseph F. Hayes
, Adrian Heald
, Oliver D. Howes
, John M. Kane
, Maria Kapi

Stefan Leucht, Nicholas Meyer, Brian O'Donoghue, Emmanuel Okeke, Benjamin I. Perry, Marco Solmi, Iris E. Sommer, Vivek Srivastava, Heidi Taipale, David Taylor, Jari Tiihonen, Allan H. Young, Najma Siddiqi, Dan Siskind, Simon Rosenbaum, Cherrie Galletly, Stephanie Allan, Constanza Caneo, Rebekah Carney, Andre F. Carvalho, Mary Lou Chatterton, Jackie Curtis, Erin Hoare, Sarah E. Jackson, Steve Kisely, Karina Lovell, Patrick D. McGorry, Cathrine Mihalopoulos, Toby Pillinger, Jerome Sarris, Felipe B. Schuch, David Shiers, Lee Smith, Shuichi Suetani, Johanna Taylor, Scott B. Teasdale, Graham Thornicroft, John Torous, Tim Usherwood, Davy Vancampfort, Nicola Veronese, Philip B. Ward, Alison R. Yung, Eóin Killackey, Brendon Stubbs, Robert A. McCutcheon

^*Corresponding author for this work

Metro South Addiction and Mental Health Service
Faculty of Medicine
University of Queensland
University of Oxford
Centre for Addiction and Mental Health
University of Toronto
University Health Network, Toronto
University of Hong Kong
Queens Medical Centre
Warneford Hospital
Zucker Hillside Hospital
Zucker School of Medicine
Feinstein Institute for Medical Research
Institute for Radiology, CCM
German Center for Mental Health (DZPG)
Pontificia Universidad Catolica de Chile
Department of Translational Biomedicine and Neuroscience
Biotechnologies and Biopharmaceutics University of Bari
King's College London
Stellenbosch University, Faculty of Medicine and Health Sciences
University of Manchester
Manchester Academic Health Sciences Centre
SLaM South London and Maudsley NHS Foundation Trust
GSTT Guy's and St Thomas' NHS Foundation Trust
Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
UCL Faculty of Brain Sciences
North London NHS Foundation Trust
Hope Hospital
Technical University of Munich
Insomnia and Behavioural Sleep Medicine Clinic
UCL Hospitals NHS Foundation Trust
UCD University College Dublin
Birmingham Business School
Birmingham Women's NHS Foundation Trust
University of Ottawa
The Ottawa Hospital
Ottawa Hospital Research Institute
University Medical Center Groningen
PanLondon Acute Medicine Network
University of Eastern Finland
Karolinska Institute
University of Helsinki
Imperial College London

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Original language	English
Pages (from-to)	673-699
Number of pages	27
Journal	The Lancet Psychiatry
Volume	12
Issue number	9
DOIs	https://doi.org/10.1016/S2215-0366(25)00162-2
Publication status	Published - Sept 2025

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Halstead, S., Yap, C. X., Warren, N., Agarwal, S. M., Brand, B. A., Chan, S. K. W., Cipriani, A., Correll, C. U., Crossley, N., D'Ambrosio, E., Emsley, R., Firth, J., Gaughran, F., Gee, S., Hahn, M., Hayes, J. F., Heald, A., Howes, O. D., Kane, J. M., ... McCutcheon, R. A. (2025). Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission. The Lancet Psychiatry, 12(9), 673-699. https://doi.org/10.1016/S2215-0366(25)00162-2

@article{d867ef79c54944a683a30715253fef5a,

title = "Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission",

author = "Sean Halstead and Yap, \{Chloe X.\} and Nicola Warren and Agarwal, \{Sri Mahavir\} and Brand, \{Bodyl A.\} and Chan, \{Sherry Kit Wa\} and Andrea Cipriani and Correll, \{Christoph U.\} and Nicolas Crossley and Enrico D'Ambrosio and Robin Emsley and Joseph Firth and Fiona Gaughran and Siobhan Gee and Margaret Hahn and Hayes, \{Joseph F.\} and Adrian Heald and Howes, \{Oliver D.\} and Kane, \{John M.\} and Maria Kapi and Stefan Leucht and Nicholas Meyer and Brian O'Donoghue and Emmanuel Okeke and Perry, \{Benjamin I.\} and Marco Solmi and Sommer, \{Iris E.\} and Vivek Srivastava and Heidi Taipale and David Taylor and Jari Tiihonen and Young, \{Allan H.\} and Najma Siddiqi and Dan Siskind and Simon Rosenbaum and Cherrie Galletly and Stephanie Allan and Constanza Caneo and Rebekah Carney and Carvalho, \{Andre F.\} and Chatterton, \{Mary Lou\} and Jackie Curtis and Erin Hoare and Jackson, \{Sarah E.\} and Steve Kisely and Karina Lovell and McGorry, \{Patrick D.\} and Cathrine Mihalopoulos and Toby Pillinger and Jerome Sarris and Schuch, \{Felipe B.\} and David Shiers and Lee Smith and Shuichi Suetani and Johanna Taylor and Teasdale, \{Scott B.\} and Graham Thornicroft and John Torous and Tim Usherwood and Davy Vancampfort and Nicola Veronese and Ward, \{Philip B.\} and Yung, \{Alison R.\} and E{\'o}in Killackey and Brendon Stubbs and McCutcheon, \{Robert A.\}",

year = "2025",

month = sep,

doi = "10.1016/S2215-0366(25)00162-2",

language = "English",

volume = "12",

pages = "673--699",

journal = "The Lancet Psychiatry",

issn = "2215-0366",

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}

Halstead, S, Yap, CX, Warren, N, Agarwal, SM, Brand, BA, Chan, SKW, Cipriani, A, Correll, CU, Crossley, N, D'Ambrosio, E, Emsley, R, Firth, J, Gaughran, F , Gee, S, Hahn, M, Hayes, JF, Heald, A, Howes, OD, Kane, JM, Kapi, M, Leucht, S, Meyer, N, O'Donoghue, B, Okeke, E, Perry, BI, Solmi, M, Sommer, IE, Srivastava, V, Taipale, H, Taylor, D, Tiihonen, J, Young, AH, Siddiqi, N, Siskind, D, Rosenbaum, S, Galletly, C, Allan, S, Caneo, C, Carney, R, Carvalho, AF, Chatterton, ML, Curtis, J, Hoare, E, Jackson, SE, Kisely, S, Lovell, K, McGorry, PD, Mihalopoulos, C, Pillinger, T, Sarris, J, Schuch, FB, Shiers, D, Smith, L, Suetani, S, Taylor, J, Teasdale, SB, Thornicroft, G, Torous, J, Usherwood, T, Vancampfort, D, Veronese, N, Ward, PB, Yung, AR, Killackey, E, Stubbs, B & McCutcheon, RA 2025, 'Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission', The Lancet Psychiatry, vol. 12, no. 9, pp. 673-699. https://doi.org/10.1016/S2215-0366(25)00162-2

TY - JOUR

T1 - Holistic prevention and management of physical health side-effects of psychotropic medication

T2 - second report of the Lancet Psychiatry Physical Health Commission

AU - Halstead, Sean

AU - Yap, Chloe X.

AU - Warren, Nicola

AU - Agarwal, Sri Mahavir

AU - Brand, Bodyl A.

AU - Chan, Sherry Kit Wa

AU - Cipriani, Andrea

AU - Correll, Christoph U.

AU - Crossley, Nicolas

AU - D'Ambrosio, Enrico

AU - Emsley, Robin

AU - Firth, Joseph

AU - Gaughran, Fiona

AU - Gee, Siobhan

AU - Hahn, Margaret

AU - Hayes, Joseph F.

AU - Heald, Adrian

AU - Howes, Oliver D.

AU - Kane, John M.

AU - Kapi, Maria

AU - Leucht, Stefan

AU - Meyer, Nicholas

AU - O'Donoghue, Brian

AU - Okeke, Emmanuel

AU - Perry, Benjamin I.

AU - Solmi, Marco

AU - Sommer, Iris E.

AU - Srivastava, Vivek

AU - Taipale, Heidi

AU - Taylor, David

AU - Tiihonen, Jari

AU - Young, Allan H.

AU - Siddiqi, Najma

AU - Siskind, Dan

AU - Rosenbaum, Simon

AU - Galletly, Cherrie

AU - Allan, Stephanie

AU - Caneo, Constanza

AU - Carney, Rebekah

AU - Carvalho, Andre F.

AU - Chatterton, Mary Lou

AU - Curtis, Jackie

AU - Hoare, Erin

AU - Jackson, Sarah E.

AU - Kisely, Steve

AU - Lovell, Karina

AU - McGorry, Patrick D.

AU - Mihalopoulos, Cathrine

AU - Pillinger, Toby

AU - Sarris, Jerome

AU - Schuch, Felipe B.

AU - Shiers, David

AU - Smith, Lee

AU - Suetani, Shuichi

AU - Taylor, Johanna

AU - Teasdale, Scott B.

AU - Thornicroft, Graham

AU - Torous, John

AU - Usherwood, Tim

AU - Vancampfort, Davy

AU - Veronese, Nicola

AU - Ward, Philip B.

AU - Yung, Alison R.

AU - Killackey, Eóin

AU - Stubbs, Brendon

AU - McCutcheon, Robert A.

PY - 2025/9

Y1 - 2025/9

UR - https://www.scopus.com/pages/publications/105013131582

U2 - 10.1016/S2215-0366(25)00162-2

DO - 10.1016/S2215-0366(25)00162-2

M3 - Review article

C2 - 40812961

AN - SCOPUS:105013131582

SN - 2215-0366

VL - 12

SP - 673

EP - 699

JO - The Lancet Psychiatry

JF - The Lancet Psychiatry

IS - 9

ER -

Holistic prevention and management of physical health side-effects of psychotropic medication: second report of the Lancet Psychiatry Physical Health Commission

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