How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

TY - JOUR

T1 - How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

AU - Shankar-Hari, Manu

AU - Lord, Graham M.

PY - 2014/4/1

Y1 - 2014/4/1

N2 - Sepsis is a heterogeneous illness characterised by inflammation secondary to suspected or proven infection. A clinical and research challenge in this area is the ability to diagnose true sepsis, defined as inflammation secondary to infection. Infection is often indirectly confirmed using surrogates, whilst awaiting microbiological confirmation. microRNAs are novel molecules with a potential to be point of care rapid diagnostic test for true sepsis.

AB - Sepsis is a heterogeneous illness characterised by inflammation secondary to suspected or proven infection. A clinical and research challenge in this area is the ability to diagnose true sepsis, defined as inflammation secondary to infection. Infection is often indirectly confirmed using surrogates, whilst awaiting microbiological confirmation. microRNAs are novel molecules with a potential to be point of care rapid diagnostic test for true sepsis.

KW - micrornas

KW - infection

KW - diagnosis

KW - humans

KW - sepsis

KW - ORGAN FAILURE

KW - BIOMARKERS

KW - THERAPY

U2 - 10.1586/14737159.2014.899151

DO - 10.1586/14737159.2014.899151

M3 - Editorial

SN - 1473-7159

VL - 14

SP - 249

EP - 251

JO - EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

JF - EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

IS - 3

ER -