How to predict proliferative vitreoretinopathy: a prospective study

R H Asaria, C H Kon, C Bunce, D G Charteris, D Wong, P J Luthert, P T Khaw, G W Aylward

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)

Abstract

PURPOSE: To determine prospectively the accuracy of a predictive risk formula for the development of postoperative proliferative vitreoretinopathy (PVR) when applied in a clinical setting.

DESIGN: Prospective noncomparative interventional case series.

PARTICIPANTS: Two hundred nineteen subjects undergoing primary vitrectomy for rhegmatogenous retinal detachment were studied.

METHOD: By use of a formula-based discriminant rule, subjects were classified as either high or low risk for the development of PVR. All subjects were followed prospectively.

OUTCOME MEASURES: Development of postoperative PVR as defined by the updated the Retina Society Classification.

RESULTS: Complete data were available on 212 of 219 subjects. There were 130 subjects identified as low risk and 82 subjects as high risk; 9.2% of the low-risk (12 of 130) compared with 28% (23 of 82) of the high-risk subjects had postoperative PVR develop. This difference was statistically significant (P < 0.001).

CONCLUSIONS: Our study has shown that using a clinical model it is possible to identify subjects at greater risk of PVR developing after primary vitrectomy.

Original languageEnglish
Pages (from-to)1184-6
Number of pages3
JournalOphthalmology
Volume108
Issue number7
Publication statusPublished - Jul 2001

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Diagnostic Techniques, Ophthalmological
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Reproducibility of Results
  • Retinal Detachment
  • Risk Factors
  • Vitrectomy
  • Vitreoretinopathy, Proliferative
  • Clinical Trial
  • Journal Article
  • Research Support, Non-U.S. Gov't

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