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Hybrid Mass Spectrometry: Towards Characterization of Protein Conformational States

Research output: Contribution to journalArticle

Original languageEnglish
JournalTRENDS IN BIOCHEMICAL SCIENCES
DOIs
E-pub ahead of print17 May 2016

Documents

  • TIBS_1252

    TIBS_1252.pdf, 1.38 MB, application/pdf

    Uploaded date:18 May 2016

    Version:Accepted author manuscript

King's Authors

Abstract

A current challenge in structural biology is to unravel the conformational states of protein complexes. Hybrid mass spectrometry (MS) has emerged as a key tool to study the structural dynamics of large protein complexes unattainable by traditional methods. Here, we discuss recent advances in hybrid MS allowing characterization of challenging biological systems.

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