Image registration of structural and physiological MR images of abnormal anatomy

Andreas Mang, Oscar Camara, Gisele Brasil Caseiras, William R. Crum, Julia A. Schnabel, Thorsten M. Buzug, John Thornton, H. Rolf Jaeger, David J. Hawkes

Research output: Chapter in Book/Report/Conference proceedingConference paper


This study applies image registration techniques to combine functional and structural information derived from multi-modal magnetic resonance imaging in patients diagnosed with brain gliomas. The images vary substantially in resolution, signal-to-noise ratio, information content and field of view and therefore pose a challenging registration problem. Specific protocols have been designed for each registration task, with careful selection of critical parameters and appropriate pre-processing. In addition, we have developed a visual assessment protocol to evaluate the accuracy of the proposed methods. Preliminary results suggest that registrations errors are below the functional image resolutions, thus achieving sub-voxel accuracy.

Original languageEnglish
Title of host publicationAdvances in Medical Engineering
Subtitle of host publicationPart II
EditorsTM Buzug, D Holz, J Bongartz, M KohlBareis, U Hartmann
Place of PublicationBERLIN
Number of pages6
ISBN (Print)978-3-540-68763-4
Publication statusPublished - 2007

Publication series

NameSpringer Proceedings in Physics
ISSN (Print)0930-8989


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