Imaging Biomarkers in Oncology: Basics and Application to Magnetic Resonance Imaging (MRI)

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Abstract

Cancer remains a global killer alongside cardiovascular disease. A better understanding of cancer biology has transformed its management with an increasing emphasis on a personalized approach, so-called ‘precision cancer medicine’. Imaging has a key role to play in the management of cancer patients. Imaging biomarkers that objectively inform on tumor biology, the tumor environment, and tumor changes in response to an intervention complement genomic and molecular diagnostics. In this review we describe the key principles for imaging biomarker development and discuss the current status with respect to magnetic resonance imaging (MRI).

Original languageEnglish
Pages (from-to)13-26
JournalJournal of Magnetic Resonance Imaging
Volume48
Issue number1
Early online date3 Jul 2018
DOIs
Publication statusE-pub ahead of print - 3 Jul 2018

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