TY - JOUR
T1 - Imaging Cancer Metabolism with Positron Emission Tomography (PET)
AU - Witney, Timothy H
AU - Lewis, David Y
PY - 2019
Y1 - 2019
N2 - Positron emission tomography (PET) enables the noninvasive spatiotemporal analysis of cancer metabolism in vivo. Both natural and nonnatural PET tracers have been developed to assess metabolic pathways during tumorigenesis, cancer progression, and metastasis. Here we describe the dynamic in vivo PET/CT imaging of the glucose analogue [18F]fluoro-2-deoxy-D-glucose (FDG), taking into consideration the methodology for alternative metabolic PET substrates.
AB - Positron emission tomography (PET) enables the noninvasive spatiotemporal analysis of cancer metabolism in vivo. Both natural and nonnatural PET tracers have been developed to assess metabolic pathways during tumorigenesis, cancer progression, and metastasis. Here we describe the dynamic in vivo PET/CT imaging of the glucose analogue [18F]fluoro-2-deoxy-D-glucose (FDG), taking into consideration the methodology for alternative metabolic PET substrates.
UR - http://www.scopus.com/inward/record.url?scp=85061145806&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-9027-6_2
DO - 10.1007/978-1-4939-9027-6_2
M3 - Article
C2 - 30725448
SN - 1940-6029
VL - 1928
SP - 29
EP - 44
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -