Immune mechanisms of food allergy and its prevention by early intervention

    Research output: Contribution to journalArticlepeer-review

    30 Citations (Scopus)
    149 Downloads (Pure)


    The environmental factors driving the increase in food allergies are unclear and possibly involve dual exposure to allergens, microbiome-driven effects or other mechanisms. Until they can be better understood, early intervention aiming at establishing oral tolerance provides an effective way to decrease the window-of-risk when children may develop allergic sensitisation to foods due to the absence of a protective immune response. Thus, the recent LEAP (Learning Early About Peanut allergy) and LEAP-On studies achieved a high level of peanut allergy prevention by early introduction of peanuts in the infants diet and conveyed more information regarding the evolution of IgE and IgG4 antibody responses to food antigens over time.
    Original languageEnglish
    Pages (from-to)92-98
    Number of pages7
    JournalCurrent Opinion in Immunology
    Early online date9 Sept 2017
    Publication statusE-pub ahead of print - 9 Sept 2017


    Dive into the research topics of 'Immune mechanisms of food allergy and its prevention by early intervention'. Together they form a unique fingerprint.

    Cite this