IMMUNOLOGY Allergy's Achilles' heel?

Brian J. Sutton*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

1 Citation (Scopus)

Abstract

Allergic reactions to otherwise innocuous substances involve a complex interplay of molecular interactions-some strong, some weak. This study reveals a key role for low-affinity antibodies and thus a possible point of weakness that may be exploited for therapeutic intervention.

Original languageEnglish
Article numberN/A
Pages (from-to)756-759
Number of pages4
JournalNature Chemical Biology
Volume9
Issue number12
DOIs
Publication statusPublished - Dec 2013

Keywords

  • MAST-CELLS
  • IGE
  • RECEPTOR
  • DEGRANULATION
  • BINDING

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