Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis

TY - JOUR

T1 - Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis

AU - Grundy, Myriam M L

AU - Wilde, Peter J.

AU - Butterworth, Peter J.

AU - Gray, Robert

AU - Ellis, Peter R.

PY - 2015/10/15

Y1 - 2015/10/15

N2 - Although almonds have a high lipid content, their consumption is associated with reduced risk of cardiovascular disease. One explanation for this paradox could be limited bioaccessibility of almond lipids due to the cell wall matrix acting as a physical barrier to digestion in the upper gastrointestinal tract. We aimed to measure the rate and extent of lipolysis in an in vitro duodenum digestion model, using raw and roasted almond materials with potentially different degrees of bioaccessibility. The results revealed that a decrease in particle size led to an increased rate and extent of lipolysis. Particle size had a crucial impact on lipid bioaccessibility, since it is an indicator of the proportion of ruptured cells in the almond tissue. Separated almond cells with intact cell walls showed the lowest levels of digestibility. This study underlines the importance of the cell wall for modulating lipid uptake and hence the positive health benefits underlying almond consumption.

AB - Although almonds have a high lipid content, their consumption is associated with reduced risk of cardiovascular disease. One explanation for this paradox could be limited bioaccessibility of almond lipids due to the cell wall matrix acting as a physical barrier to digestion in the upper gastrointestinal tract. We aimed to measure the rate and extent of lipolysis in an in vitro duodenum digestion model, using raw and roasted almond materials with potentially different degrees of bioaccessibility. The results revealed that a decrease in particle size led to an increased rate and extent of lipolysis. Particle size had a crucial impact on lipid bioaccessibility, since it is an indicator of the proportion of ruptured cells in the almond tissue. Separated almond cells with intact cell walls showed the lowest levels of digestibility. This study underlines the importance of the cell wall for modulating lipid uptake and hence the positive health benefits underlying almond consumption.

KW - Almond

KW - Encapsulation

KW - Lipid bioaccessibility

KW - Lipolysis

KW - Plant cell walls

UR - http://www.scopus.com/inward/record.url?scp=84927762695&partnerID=8YFLogxK

U2 - 10.1016/j.foodchem.2015.04.013

DO - 10.1016/j.foodchem.2015.04.013

M3 - Article

AN - SCOPUS:84927762695

SN - 0308-8146

VL - 185

SP - 405

EP - 412

JO - FOOD CHEMISTRY

JF - FOOD CHEMISTRY

ER -