TY - JOUR
T1 - Impact of COVID-19 on gestational diabetes pregnancy outcomes in the UK
T2 - A multicentre retrospective cohort study
AU - Mclennan, Niamh Maire
AU - Lindsay, Robert
AU - Saravanan, Ponnusamy
AU - Sukumar, Nithya
AU - White, Sara L.
AU - von Dadelszen, Peter
AU - Burden, Christy
AU - Hunt, Kathryn
AU - George, Priya
AU - Hirst, Jane E.
AU - Lattey, Katherine
AU - Lee, Tara T.M.
AU - Murphy, Helen R.
AU - Scott, Eleanor M.
AU - Magee, Laura A.
AU - Reynolds, Rebecca M.
N1 - Funding Information:
No funding was received for this study. N‐MM and RMR acknowledge the support of the British Heart Foundation (RE/18/5/34216). TL acknowledges the support of the Diabetes Research & Wellness Foundation Sutherland‐Earl Clinical Fellowship (SECF/21).
Publisher Copyright:
© 2023 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.
PY - 2023/11/15
Y1 - 2023/11/15
N2 - Objective: To determine the impact of implementing emergency care pathway(s) for screening, diagnosing and managing women with gestational diabetes (GDM) during COVID-19. Design: Retrospective multicentre cohort. Setting: Nine National Health Service (NHS) Hospital Trusts/Health boards in England and Scotland. Population: 4915 women with GDM pre-pandemic (1 April 2018 to 31 March 2020), and 3467 women with GDM during the pandemic (1 May 2020 to 31 March 2021). Methods: We examined clinical outcomes for women with GDM prior to and during the pandemic following changes in screening methods, diagnostic testing, glucose thresholds and introduction of virtual care for monitoring of antenatal glycaemia. Main Outcome Measures: Intervention at birth, perinatal mortality, large-for-gestational-age infants and neonatal unit admission. Results: The new diagnostic criteria more often identified GDM women who were multiparous, had higher body mass index (BMI) and greater deprivation, and less frequently had previous GDM (all p < 0.05). During COVID, these women had no differences in the key outcome measures. Of the women, 3% were identified with pre-existing diabetes at antenatal booking. Where OGTT continued during COVID, but virtual care was introduced, outcomes were also similar pre- and during the pandemic. Conclusions: Using HbA1c and fasting glucose identified a higher risk GDM population during the pandemic but this had minimal impact on pregnancy outcomes. The high prevalence of undiagnosed pre-existing diabetes suggests that women with GDM risk factors should be offered HbA1c screening in early pregnancy.
AB - Objective: To determine the impact of implementing emergency care pathway(s) for screening, diagnosing and managing women with gestational diabetes (GDM) during COVID-19. Design: Retrospective multicentre cohort. Setting: Nine National Health Service (NHS) Hospital Trusts/Health boards in England and Scotland. Population: 4915 women with GDM pre-pandemic (1 April 2018 to 31 March 2020), and 3467 women with GDM during the pandemic (1 May 2020 to 31 March 2021). Methods: We examined clinical outcomes for women with GDM prior to and during the pandemic following changes in screening methods, diagnostic testing, glucose thresholds and introduction of virtual care for monitoring of antenatal glycaemia. Main Outcome Measures: Intervention at birth, perinatal mortality, large-for-gestational-age infants and neonatal unit admission. Results: The new diagnostic criteria more often identified GDM women who were multiparous, had higher body mass index (BMI) and greater deprivation, and less frequently had previous GDM (all p < 0.05). During COVID, these women had no differences in the key outcome measures. Of the women, 3% were identified with pre-existing diabetes at antenatal booking. Where OGTT continued during COVID, but virtual care was introduced, outcomes were also similar pre- and during the pandemic. Conclusions: Using HbA1c and fasting glucose identified a higher risk GDM population during the pandemic but this had minimal impact on pregnancy outcomes. The high prevalence of undiagnosed pre-existing diabetes suggests that women with GDM risk factors should be offered HbA1c screening in early pregnancy.
KW - COVID-19
KW - gestational diabetes
UR - http://www.scopus.com/inward/record.url?scp=85176933445&partnerID=8YFLogxK
U2 - 10.1111/1471-0528.17716
DO - 10.1111/1471-0528.17716
M3 - Article
AN - SCOPUS:85176933445
SN - 1470-0328
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
ER -