Implanted cortical neuroprosthetics for speech and movement restoration

William R. Muirhead; Hugo Layard Horsfall; Christine Aicardi; Jacques Carolan; Harith Akram; Anne Vanhoestenberghe; Andreas T. Schaefer; Hani J. Marcus

doi:10.1007/s00415-024-12604-w

Implanted cortical neuroprosthetics for speech and movement restoration

William R. Muirhead^*, Hugo Layard Horsfall, Christine Aicardi, Jacques Carolan, Harith Akram, Anne Vanhoestenberghe, Andreas T. Schaefer, Hani J. Marcus

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

Implanted cortical neuroprosthetics (ICNs) are medical devices developed to replace dysfunctional neural pathways by creating information exchange between the brain and a digital system which can facilitate interaction with the external world. Over the last decade, researchers have explored the application of ICNs for diverse conditions including blindness, aphasia, and paralysis. Both transcranial and endovascular approaches have been used to record neural activity in humans, and in a laboratory setting, high-performance decoding of the signals associated with speech intention has been demonstrated. Particular progress towards a device which can move into clinical practice has been made with ICNs focussed on the restoration of speech and movement. This article provides an overview of contemporary ICNs for speech and movement restoration, their mechanisms of action and the unique ethical challenges raised by the field.

Original language	English
Pages (from-to)	7156-7168
Number of pages	13
Journal	Journal of Neurology
Volume	271
Issue number	11
DOIs	https://doi.org/10.1007/s00415-024-12604-w
Publication status	Published - 24 Oct 2024

Keywords

Brain–computer interface
Motor neuroprosthesis
Neurological disease
Neuromotor prosthesis
Neuroprosthetic
Neurotechnology

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10.1007/s00415-024-12604-w

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title = "Implanted cortical neuroprosthetics for speech and movement restoration",

abstract = "Implanted cortical neuroprosthetics (ICNs) are medical devices developed to replace dysfunctional neural pathways by creating information exchange between the brain and a digital system which can facilitate interaction with the external world. Over the last decade, researchers have explored the application of ICNs for diverse conditions including blindness, aphasia, and paralysis. Both transcranial and endovascular approaches have been used to record neural activity in humans, and in a laboratory setting, high-performance decoding of the signals associated with speech intention has been demonstrated. Particular progress towards a device which can move into clinical practice has been made with ICNs focussed on the restoration of speech and movement. This article provides an overview of contemporary ICNs for speech and movement restoration, their mechanisms of action and the unique ethical challenges raised by the field.",

keywords = "Brain–computer interface, Motor neuroprosthesis, Neurological disease, Neuromotor prosthesis, Neuroprosthetic, Neurotechnology",

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AU - Muirhead, William R.

AU - Layard Horsfall, Hugo

AU - Aicardi, Christine

AU - Carolan, Jacques

AU - Akram, Harith

AU - Vanhoestenberghe, Anne

AU - Schaefer, Andreas T.

AU - Marcus, Hani J.

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/10/24

Y1 - 2024/10/24

N2 - Implanted cortical neuroprosthetics (ICNs) are medical devices developed to replace dysfunctional neural pathways by creating information exchange between the brain and a digital system which can facilitate interaction with the external world. Over the last decade, researchers have explored the application of ICNs for diverse conditions including blindness, aphasia, and paralysis. Both transcranial and endovascular approaches have been used to record neural activity in humans, and in a laboratory setting, high-performance decoding of the signals associated with speech intention has been demonstrated. Particular progress towards a device which can move into clinical practice has been made with ICNs focussed on the restoration of speech and movement. This article provides an overview of contemporary ICNs for speech and movement restoration, their mechanisms of action and the unique ethical challenges raised by the field.

AB - Implanted cortical neuroprosthetics (ICNs) are medical devices developed to replace dysfunctional neural pathways by creating information exchange between the brain and a digital system which can facilitate interaction with the external world. Over the last decade, researchers have explored the application of ICNs for diverse conditions including blindness, aphasia, and paralysis. Both transcranial and endovascular approaches have been used to record neural activity in humans, and in a laboratory setting, high-performance decoding of the signals associated with speech intention has been demonstrated. Particular progress towards a device which can move into clinical practice has been made with ICNs focussed on the restoration of speech and movement. This article provides an overview of contemporary ICNs for speech and movement restoration, their mechanisms of action and the unique ethical challenges raised by the field.

KW - Brain–computer interface

KW - Motor neuroprosthesis

KW - Neurological disease

KW - Neuromotor prosthesis

KW - Neuroprosthetic

KW - Neurotechnology

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M3 - Review article

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AN - SCOPUS:85207715715

SN - 0340-5354

VL - 271

SP - 7156

EP - 7168

JO - Journal of Neurology

JF - Journal of Neurology

IS - 11

ER -

Implanted cortical neuroprosthetics for speech and movement restoration

Abstract

Keywords

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