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Implants and depot injections for treating opioid dependence: qualitative study of people who use or have used heroin

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Implants and depot injections for treating opioid dependence : qualitative study of people who use or have used heroin. / Neale, Joanne; Tompkins, Charlotte N. E.; McDonald, Rebecca; Strang, John.

In: Drug and alcohol dependence, Vol. 189, No. 1, 01.08.2018.

Research output: Contribution to journalArticle

Harvard

Neale, J, Tompkins, CNE, McDonald, R & Strang, J 2018, 'Implants and depot injections for treating opioid dependence: qualitative study of people who use or have used heroin', Drug and alcohol dependence, vol. 189, no. 1. https://doi.org/10.1016/j.drugalcdep.2018.03.057

APA

Neale, J., Tompkins, C. N. E., McDonald, R., & Strang, J. (2018). Implants and depot injections for treating opioid dependence: qualitative study of people who use or have used heroin. Drug and alcohol dependence, 189(1). https://doi.org/10.1016/j.drugalcdep.2018.03.057

Vancouver

Neale J, Tompkins CNE, McDonald R, Strang J. Implants and depot injections for treating opioid dependence: qualitative study of people who use or have used heroin. Drug and alcohol dependence. 2018 Aug 1;189(1). https://doi.org/10.1016/j.drugalcdep.2018.03.057

Author

Neale, Joanne ; Tompkins, Charlotte N. E. ; McDonald, Rebecca ; Strang, John. / Implants and depot injections for treating opioid dependence : qualitative study of people who use or have used heroin. In: Drug and alcohol dependence. 2018 ; Vol. 189, No. 1.

Bibtex Download

@article{d42c084992e04e38bce20340af091afa,
title = "Implants and depot injections for treating opioid dependence: qualitative study of people who use or have used heroin",
abstract = "BackgroundLong-acting opioid pharmacotherapy (OPT) is presumed to offer benefits over more conventional OPT formulations. This paper analyzes the views and experiences of people who use or have used heroin in order to explore two novel systems for delivering long-acting OPT: implants and depot injections. New materialism theorizing is used to interpret and frame the findings.MethodsQualitative data were generated via seven focus groups conducted during 2017 in London, UK. Participants (n = 44; 28 men and 16 women; ages 33–66 years) had all received OPT. Focus group discussions covered real and potential OPT delivery systems. All participant data relating to implants and depot injections were coded using MAXQDA software and analysed inductively via Iterative Categorisation.FindingsParticipants discussed implants and depot injections in terms of interacting physical, psychological and social factors: dose stability; OPT administration; stopping treatment; co-presence of an antagonist; breaking rituals and habits; reduced choice and control; feeling normal; information needs; getting on with everyday life; and social interaction. Participants identified both benefits and concerns, and variable needs and preferences, with respect to each delivery system.ConclusionsImplants and depot injections are not ‘fixed’ medications that can be administered to people to achieve pre-determined treatment aims. Rather, they are complex ‘assemblages’ with uncertain outcomes. Furthermore, they are themselves part of wider interactive ‘assemblages’. Drug developers and treatment providers need to understand this complexity in order to target long-acting OPT at people most likely to benefit from it, and to reduce any unintended negative consequences.",
author = "Joanne Neale and Tompkins, {Charlotte N. E.} and Rebecca McDonald and John Strang",
year = "2018",
month = "8",
day = "1",
doi = "10.1016/j.drugalcdep.2018.03.057",
language = "English",
volume = "189",
journal = "Drug and alcohol dependence",
issn = "0376-8716",
number = "1",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Implants and depot injections for treating opioid dependence

T2 - qualitative study of people who use or have used heroin

AU - Neale, Joanne

AU - Tompkins, Charlotte N. E.

AU - McDonald, Rebecca

AU - Strang, John

PY - 2018/8/1

Y1 - 2018/8/1

N2 - BackgroundLong-acting opioid pharmacotherapy (OPT) is presumed to offer benefits over more conventional OPT formulations. This paper analyzes the views and experiences of people who use or have used heroin in order to explore two novel systems for delivering long-acting OPT: implants and depot injections. New materialism theorizing is used to interpret and frame the findings.MethodsQualitative data were generated via seven focus groups conducted during 2017 in London, UK. Participants (n = 44; 28 men and 16 women; ages 33–66 years) had all received OPT. Focus group discussions covered real and potential OPT delivery systems. All participant data relating to implants and depot injections were coded using MAXQDA software and analysed inductively via Iterative Categorisation.FindingsParticipants discussed implants and depot injections in terms of interacting physical, psychological and social factors: dose stability; OPT administration; stopping treatment; co-presence of an antagonist; breaking rituals and habits; reduced choice and control; feeling normal; information needs; getting on with everyday life; and social interaction. Participants identified both benefits and concerns, and variable needs and preferences, with respect to each delivery system.ConclusionsImplants and depot injections are not ‘fixed’ medications that can be administered to people to achieve pre-determined treatment aims. Rather, they are complex ‘assemblages’ with uncertain outcomes. Furthermore, they are themselves part of wider interactive ‘assemblages’. Drug developers and treatment providers need to understand this complexity in order to target long-acting OPT at people most likely to benefit from it, and to reduce any unintended negative consequences.

AB - BackgroundLong-acting opioid pharmacotherapy (OPT) is presumed to offer benefits over more conventional OPT formulations. This paper analyzes the views and experiences of people who use or have used heroin in order to explore two novel systems for delivering long-acting OPT: implants and depot injections. New materialism theorizing is used to interpret and frame the findings.MethodsQualitative data were generated via seven focus groups conducted during 2017 in London, UK. Participants (n = 44; 28 men and 16 women; ages 33–66 years) had all received OPT. Focus group discussions covered real and potential OPT delivery systems. All participant data relating to implants and depot injections were coded using MAXQDA software and analysed inductively via Iterative Categorisation.FindingsParticipants discussed implants and depot injections in terms of interacting physical, psychological and social factors: dose stability; OPT administration; stopping treatment; co-presence of an antagonist; breaking rituals and habits; reduced choice and control; feeling normal; information needs; getting on with everyday life; and social interaction. Participants identified both benefits and concerns, and variable needs and preferences, with respect to each delivery system.ConclusionsImplants and depot injections are not ‘fixed’ medications that can be administered to people to achieve pre-determined treatment aims. Rather, they are complex ‘assemblages’ with uncertain outcomes. Furthermore, they are themselves part of wider interactive ‘assemblages’. Drug developers and treatment providers need to understand this complexity in order to target long-acting OPT at people most likely to benefit from it, and to reduce any unintended negative consequences.

U2 - 10.1016/j.drugalcdep.2018.03.057

DO - 10.1016/j.drugalcdep.2018.03.057

M3 - Article

VL - 189

JO - Drug and alcohol dependence

JF - Drug and alcohol dependence

SN - 0376-8716

IS - 1

ER -

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