In vitro antiplasmodial activity of extracts of Argentinian plants

TY - JOUR

T1 - In vitro antiplasmodial activity of extracts of Argentinian plants

AU - Debenedetti, S

AU - Muschietti, L

AU - van Baren, C

AU - Clavin, M

AU - Broussalis, A

AU - Martino, V

AU - Houghton, P J

AU - Warhurst, D

AU - Steele, J

PY - 2002

Y1 - 2002

N2 - Fifteen extracts from nine selected Argentine medicinal plants were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]-hypoxan thine into the Plasmoditan falciparum K 1 pyrimethamine/chloroquine resistant strain. The methanol extract of Satureja parvifolia showed good antiplasmodial activity (IC50 3 mug/ml). Inhibition of the growth of P. falciparum was also observed with aqueous extracts of Buddleja globosa and S. parvifolia. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

AB - Fifteen extracts from nine selected Argentine medicinal plants were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]-hypoxan thine into the Plasmoditan falciparum K 1 pyrimethamine/chloroquine resistant strain. The methanol extract of Satureja parvifolia showed good antiplasmodial activity (IC50 3 mug/ml). Inhibition of the growth of P. falciparum was also observed with aqueous extracts of Buddleja globosa and S. parvifolia. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=0036243938&partnerID=8YFLogxK

U2 - 10.1016/S0378-8741(02)00024-7

DO - 10.1016/S0378-8741(02)00024-7

M3 - Article

VL - 80

SP - 163

EP - 166

JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

IS - 2-3

ER -