In vivo effects of estrogen on human brain

G Panzica (Editor), R C Melcangi, R Norbury, D M Robertson, M Whitehead, D G Murphy

Research output: Chapter in Book/Report/Conference proceedingConference paper

15 Citations (Scopus)

Abstract

Age-related brain disorders such as Alzheimer's disease (AD) are becoming increasingly prevalent. Estrogen replacement therapy (ERT) has shown potential both as a preventive measure and treatment for such disorders. Good evidence from basic science demonstrates that estrogen has multiple protective effects on neurons and neurotransmitter systems, and the effects of ERT can be demonstrated on the human brain using techniques such as functional neuroimaging. However, the evidence for estrogen's having a clinical role in the treatment and prevention of neuropsychiatric disorders is not well established. In this article we review research into the effects of estrogen on the human brain and we consider the role for ERT as a therapeutic tool.
Original languageEnglish
Title of host publicationAnn.NY Acad.Sci.
Place of PublicationNEW YORK
PublisherNew York Acad Sciences
Pages79 - 88
Number of pages10
ISBN (Print)1-57331-486-2
Publication statusPublished - 2003
Event2nd International Meeting on Steroids and the Nervous System - Turin, Italy
Duration: 1 Jan 2003 → …

Publication series

NameANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Conference

Conference2nd International Meeting on Steroids and the Nervous System
Country/TerritoryItaly
CityTurin
Period1/01/2003 → …

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