In vivo strain assessment of the abdominal aortic aneurysm

TY - JOUR

T1 - In vivo strain assessment of the abdominal aortic aneurysm

AU - Satriano, Alessandro

AU - Rivolo, Simone

AU - Martufi, Giampaolo

AU - Finol, Ender A.

AU - Di Martino, Elena S.

PY - 2015/1/21

Y1 - 2015/1/21

N2 - The only criteria currently used to inform surgical decision for abdominal aortic aneurysms are maximum diameter (>5.5. cm) and rate of growth, even though several studies have identified the need for more specific indicators of risk. Patient-specific biomechanical variables likely to affect rupture risk would be a valuable addition to the science of understanding rupture risk and prove to be a life saving benefit for patients. Local deformability of the aorta is related to the local mechanical properties of the wall and may provide indication on the state of weakening of the wall tissue. We propose a 3D image-based approach to compute aortic wall strain maps in vivo. The method is applicable to a variety of imaging modalities that provide sequential images at different phases in the cardiac cycle. We applied the method to a series of abdominal aneurysms imaged using cine-MRI obtaining strain maps at different phases in the cardiac cycle. These maps could be used to evaluate the distensibility of an aneurysm at baseline and at different follow-up times and provide an additional index to clinicians to facilitate decisions on the best course of action for a specific patient.

AB - The only criteria currently used to inform surgical decision for abdominal aortic aneurysms are maximum diameter (>5.5. cm) and rate of growth, even though several studies have identified the need for more specific indicators of risk. Patient-specific biomechanical variables likely to affect rupture risk would be a valuable addition to the science of understanding rupture risk and prove to be a life saving benefit for patients. Local deformability of the aorta is related to the local mechanical properties of the wall and may provide indication on the state of weakening of the wall tissue. We propose a 3D image-based approach to compute aortic wall strain maps in vivo. The method is applicable to a variety of imaging modalities that provide sequential images at different phases in the cardiac cycle. We applied the method to a series of abdominal aneurysms imaged using cine-MRI obtaining strain maps at different phases in the cardiac cycle. These maps could be used to evaluate the distensibility of an aneurysm at baseline and at different follow-up times and provide an additional index to clinicians to facilitate decisions on the best course of action for a specific patient.

KW - Abdominal aortic aneurysm

KW - Deformation maps

KW - Imaging

UR - http://www.scopus.com/inward/record.url?scp=84920273974&partnerID=8YFLogxK

U2 - 10.1016/j.jbiomech.2014.11.016

DO - 10.1016/j.jbiomech.2014.11.016

M3 - Article

C2 - 25497379

AN - SCOPUS:84920273974

SN - 0021-9290

VL - 48

SP - 354

EP - 360

JO - Journal of Biomechanics

JF - Journal of Biomechanics

IS - 2

ER -