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Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study

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Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. / Coupland, Victoria H; Allum, William; Blazeby, Jane M; Mendall, Michael A; Hardwick, Richard H; Linklater, Karen M; Møller, Henrik; Davies, Elizabeth A.

In: BMC Cancer, Vol. 12, No. N/A, 11, 12.01.2012, p. N/A.

Research output: Contribution to journalArticle

Harvard

Coupland, VH, Allum, W, Blazeby, JM, Mendall, MA, Hardwick, RH, Linklater, KM, Møller, H & Davies, EA 2012, 'Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study', BMC Cancer, vol. 12, no. N/A, 11, pp. N/A. https://doi.org/10.1186/1471-2407-12-11

APA

Coupland, V. H., Allum, W., Blazeby, J. M., Mendall, M. A., Hardwick, R. H., Linklater, K. M., ... Davies, E. A. (2012). Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. BMC Cancer, 12(N/A), N/A. [11]. https://doi.org/10.1186/1471-2407-12-11

Vancouver

Coupland VH, Allum W, Blazeby JM, Mendall MA, Hardwick RH, Linklater KM et al. Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. BMC Cancer. 2012 Jan 12;12(N/A):N/A. 11. https://doi.org/10.1186/1471-2407-12-11

Author

Coupland, Victoria H ; Allum, William ; Blazeby, Jane M ; Mendall, Michael A ; Hardwick, Richard H ; Linklater, Karen M ; Møller, Henrik ; Davies, Elizabeth A. / Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study. In: BMC Cancer. 2012 ; Vol. 12, No. N/A. pp. N/A.

Bibtex Download

@article{2b92c85440874a2eabb588b231f05a6f,
title = "Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study",
abstract = "Background: Major changes in the incidence of oesophageal and gastric cancers have been reported internationally. This study describes recent trends in incidence and survival of subgroups of oesophageal and gastric cancer in England between 1998 and 2007 and considers the implications for cancer services and policy.Methods: Data on 133,804 English patients diagnosed with oesophageal and gastric cancer between 1998 and 2007 were extracted from the National Cancer Data Repository. Using information on anatomical site and tumour morphology, data were divided into six groups; upper and middle oesophagus, lower oesophagus, oesophagus with an unspecified anatomical site, cardia, non-cardia stomach, and stomach with an unspecified anatomical site. Age-standardised incidence rates (per 100,000 European standard population) were calculated for each group by year of diagnosis and by socioeconomic deprivation. Survival was estimated using the Kaplan-Meier method.Results: The majority of oesophageal cancers were in the lower third of the oesophagus (58{\%}). Stomach with an unspecified anatomical site was the largest gastric cancer group (53{\%}). The incidence of lower oesophageal cancer increased between 1998 and 2002 and remained stable thereafter. The incidence of cancer of the cardia, non-cardia stomach, and stomach with an unspecified anatomical site declined over the 10 year period. Both lower oesophageal and cardia cancers had a much higher incidence in males compared with females (M:F 4:1). The incidence was also higher in the most deprived quintiles for all six cancer groups. Survival was poor in all subgroups with 1 year survival ranging from 14.8-40.8{\%} and 5 year survival ranging from 3.7-15.6{\%}.Conclusions: An increased focus on prevention and early diagnosis, especially in deprived areas and in males, is required to improve outcomes for these cancers. Improved recording of tumour site, stage and morphology and the evaluation of focused early diagnosis programmes are also needed. The poor long-term survival reinforces the need for early detection and multidisciplinary care.",
keywords = "Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Child, Child, Preschool, England, Epidemiologic Studies, Esophageal Neoplasms, Female, Humans, Incidence, Kaplan-Meier Estimate, Male, Middle Aged, Sex Distribution, Stomach Neoplasms, Survival Analysis, Young Adult",
author = "Coupland, {Victoria H} and William Allum and Blazeby, {Jane M} and Mendall, {Michael A} and Hardwick, {Richard H} and Linklater, {Karen M} and Henrik M{\o}ller and Davies, {Elizabeth A}",
year = "2012",
month = "1",
day = "12",
doi = "10.1186/1471-2407-12-11",
language = "English",
volume = "12",
pages = "N/A",
journal = "BMC Cancer",
issn = "1471-2407",
publisher = "BioMed Central",
number = "N/A",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Incidence and survival of oesophageal and gastric cancer in England between 1998 and 2007, a population-based study

AU - Coupland, Victoria H

AU - Allum, William

AU - Blazeby, Jane M

AU - Mendall, Michael A

AU - Hardwick, Richard H

AU - Linklater, Karen M

AU - Møller, Henrik

AU - Davies, Elizabeth A

PY - 2012/1/12

Y1 - 2012/1/12

N2 - Background: Major changes in the incidence of oesophageal and gastric cancers have been reported internationally. This study describes recent trends in incidence and survival of subgroups of oesophageal and gastric cancer in England between 1998 and 2007 and considers the implications for cancer services and policy.Methods: Data on 133,804 English patients diagnosed with oesophageal and gastric cancer between 1998 and 2007 were extracted from the National Cancer Data Repository. Using information on anatomical site and tumour morphology, data were divided into six groups; upper and middle oesophagus, lower oesophagus, oesophagus with an unspecified anatomical site, cardia, non-cardia stomach, and stomach with an unspecified anatomical site. Age-standardised incidence rates (per 100,000 European standard population) were calculated for each group by year of diagnosis and by socioeconomic deprivation. Survival was estimated using the Kaplan-Meier method.Results: The majority of oesophageal cancers were in the lower third of the oesophagus (58%). Stomach with an unspecified anatomical site was the largest gastric cancer group (53%). The incidence of lower oesophageal cancer increased between 1998 and 2002 and remained stable thereafter. The incidence of cancer of the cardia, non-cardia stomach, and stomach with an unspecified anatomical site declined over the 10 year period. Both lower oesophageal and cardia cancers had a much higher incidence in males compared with females (M:F 4:1). The incidence was also higher in the most deprived quintiles for all six cancer groups. Survival was poor in all subgroups with 1 year survival ranging from 14.8-40.8% and 5 year survival ranging from 3.7-15.6%.Conclusions: An increased focus on prevention and early diagnosis, especially in deprived areas and in males, is required to improve outcomes for these cancers. Improved recording of tumour site, stage and morphology and the evaluation of focused early diagnosis programmes are also needed. The poor long-term survival reinforces the need for early detection and multidisciplinary care.

AB - Background: Major changes in the incidence of oesophageal and gastric cancers have been reported internationally. This study describes recent trends in incidence and survival of subgroups of oesophageal and gastric cancer in England between 1998 and 2007 and considers the implications for cancer services and policy.Methods: Data on 133,804 English patients diagnosed with oesophageal and gastric cancer between 1998 and 2007 were extracted from the National Cancer Data Repository. Using information on anatomical site and tumour morphology, data were divided into six groups; upper and middle oesophagus, lower oesophagus, oesophagus with an unspecified anatomical site, cardia, non-cardia stomach, and stomach with an unspecified anatomical site. Age-standardised incidence rates (per 100,000 European standard population) were calculated for each group by year of diagnosis and by socioeconomic deprivation. Survival was estimated using the Kaplan-Meier method.Results: The majority of oesophageal cancers were in the lower third of the oesophagus (58%). Stomach with an unspecified anatomical site was the largest gastric cancer group (53%). The incidence of lower oesophageal cancer increased between 1998 and 2002 and remained stable thereafter. The incidence of cancer of the cardia, non-cardia stomach, and stomach with an unspecified anatomical site declined over the 10 year period. Both lower oesophageal and cardia cancers had a much higher incidence in males compared with females (M:F 4:1). The incidence was also higher in the most deprived quintiles for all six cancer groups. Survival was poor in all subgroups with 1 year survival ranging from 14.8-40.8% and 5 year survival ranging from 3.7-15.6%.Conclusions: An increased focus on prevention and early diagnosis, especially in deprived areas and in males, is required to improve outcomes for these cancers. Improved recording of tumour site, stage and morphology and the evaluation of focused early diagnosis programmes are also needed. The poor long-term survival reinforces the need for early detection and multidisciplinary care.

KW - Adolescent

KW - Adult

KW - Age Distribution

KW - Aged

KW - Aged, 80 and over

KW - Child

KW - Child, Preschool

KW - England

KW - Epidemiologic Studies

KW - Esophageal Neoplasms

KW - Female

KW - Humans

KW - Incidence

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Sex Distribution

KW - Stomach Neoplasms

KW - Survival Analysis

KW - Young Adult

U2 - 10.1186/1471-2407-12-11

DO - 10.1186/1471-2407-12-11

M3 - Article

C2 - 22239958

VL - 12

SP - N/A

JO - BMC Cancer

JF - BMC Cancer

SN - 1471-2407

IS - N/A

M1 - 11

ER -

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