TY - JOUR
T1 - Incidence of urological cancers in neurological patients
T2 - a review of the literature from the EAU Young Academic Urologist Functional Group
AU - Cancrini, Fabiana
AU - Osman, Nadir
AU - Doizi, Steeve
AU - Guillot-Tantay, Cyrille
AU - Hüsch, Tanja
AU - Illiano, Ester
AU - Tutolo, Manuela
AU - Tienza, Antonio
AU - Culha, M Gokhan
AU - Vale, Luís
AU - Raison, Nicholas
AU - Herve, François
AU - Grande, Pietro
AU - Roupret, Morgan
AU - Phé, Véronique
N1 - Publisher Copyright:
© 2023 EDIZIONI MINERVA MEDICA.
PY - 2023/4
Y1 - 2023/4
N2 - INTRODUCTION: Urological cancers can be challenging in the diagnosis and treatment of patients with neurological diseases. As a result, there are still uncertainties regarding the incidence and risk factors favouring the development of urological cancers in these patients. The aim of this study was to review the available evidence regarding the incidence for the development of urological cancers in neurological patients to provide a basis for future recommendations and research.EVIDENCE ACQUISITION: A narrative review of the literature in Medline and Scopus up to June 2019 was performed.EVIDENCE SYNTHESIS: After screening 1729 records, 30 retrospective studies were retained. For bladder cancer (BC), 21 articles were identified, including a total of 673,663 patients. Among these patients, 4744 had a diagnosis of BC (1265 females, 3214 males, gender not reported in 265). In this group, 2514 were diagnosed with BC associated with a neurological disease. For prostate cancer (PC), 14 articles were identified, including a total of 831,889 men. Among these patients, 67,543 had a diagnosis of PC and 1457 had PC and a neurological disease. Two articles reported kidney cancer (KC), one reported testicular cancer (TC) and none described penile cancer or urothelial carcinomas of the upper urinary tract in neurological patients.CONCLUSIONS: The incidence of urological cancers, especially BC and PC, in patients with neurological diseases appears comparable to the general population. However due to the paucity of studies, specific recommendations for the management are lacking in neurologically disabled patients. In this report we investigated the frequency of urinary tract cancers in patients with neurological diseases. We conclude that urological cancers, especially bladder and prostate cancer, in patients with neurological diseases occur with similar frequency as in the general population.
AB - INTRODUCTION: Urological cancers can be challenging in the diagnosis and treatment of patients with neurological diseases. As a result, there are still uncertainties regarding the incidence and risk factors favouring the development of urological cancers in these patients. The aim of this study was to review the available evidence regarding the incidence for the development of urological cancers in neurological patients to provide a basis for future recommendations and research.EVIDENCE ACQUISITION: A narrative review of the literature in Medline and Scopus up to June 2019 was performed.EVIDENCE SYNTHESIS: After screening 1729 records, 30 retrospective studies were retained. For bladder cancer (BC), 21 articles were identified, including a total of 673,663 patients. Among these patients, 4744 had a diagnosis of BC (1265 females, 3214 males, gender not reported in 265). In this group, 2514 were diagnosed with BC associated with a neurological disease. For prostate cancer (PC), 14 articles were identified, including a total of 831,889 men. Among these patients, 67,543 had a diagnosis of PC and 1457 had PC and a neurological disease. Two articles reported kidney cancer (KC), one reported testicular cancer (TC) and none described penile cancer or urothelial carcinomas of the upper urinary tract in neurological patients.CONCLUSIONS: The incidence of urological cancers, especially BC and PC, in patients with neurological diseases appears comparable to the general population. However due to the paucity of studies, specific recommendations for the management are lacking in neurologically disabled patients. In this report we investigated the frequency of urinary tract cancers in patients with neurological diseases. We conclude that urological cancers, especially bladder and prostate cancer, in patients with neurological diseases occur with similar frequency as in the general population.
KW - Male
KW - Humans
KW - Testicular Neoplasms
KW - Urologists
KW - Incidence
KW - Retrospective Studies
KW - Urologic Neoplasms/diagnosis
KW - Kidney Neoplasms/diagnosis
KW - Urinary Bladder Neoplasms
KW - Prostatic Neoplasms/diagnosis
KW - Nervous System Diseases/diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85151316547&partnerID=8YFLogxK
U2 - 10.23736/S2724-6051.23.05127-3
DO - 10.23736/S2724-6051.23.05127-3
M3 - Review article
C2 - 36999836
SN - 2724-6051
VL - 75
SP - 163
EP - 171
JO - Minerva urology and nephrology
JF - Minerva urology and nephrology
IS - 2
ER -