Inferior alveolar nerve block for the treatment of teeth presenting with irreversible pulpitis: A systematic review of the literature and meta-analysis

TY - JOUR

T1 - Inferior alveolar nerve block for the treatment of teeth presenting with irreversible pulpitis

T2 - A systematic review of the literature and meta-analysis

AU - Corbella, Stefano

AU - Taschieri, Silvio

AU - Mannocci, Francesco

AU - Rosen, Eyal

AU - Tsesis, Igor

AU - Del Fabbro, Massimo

PY - 2017

Y1 - 2017

N2 - Objective: The objective of the present systematic review was to evaluate, in patients with irreversible pulpitis affecting mandibular posterior teeth, if premedication with nonsteroidal anti-inflammatory drugs can increase the efficacy of inferior alveolar nerve block (IANB) if compared to placebo administration; if one anesthetic agent is more effective than another; if 1.8 mL injection is more effective than 3.6 mL injection to increase the efficacy of IANB; and if supplementary buccal injection is able to increase the efficacy of IANB as compared to a negative control/placebo group. Data Sources: Randomized controlled clinical trials investigating different aspects (technique, premedication with anti-inflammatory drugs, different anesthetic agents) were searched. Success of IANB, as defined in the studies, was considered as the primary outcome. A meta-analysis was performed evaluating relative risks (RRs). Electronic databases (Medline, Embase, Cochrane Central) were searched after preparation of an appropriate search string. After application of selection criteria, a total of 37 studies were included; 19 of them were considered in the meta-analysis. There was evidence of a difference in favor of the use of premedication with anti-inflammatory drugs (RR, 1.80; CI 95%, 1.50-2.14; P

AB - Objective: The objective of the present systematic review was to evaluate, in patients with irreversible pulpitis affecting mandibular posterior teeth, if premedication with nonsteroidal anti-inflammatory drugs can increase the efficacy of inferior alveolar nerve block (IANB) if compared to placebo administration; if one anesthetic agent is more effective than another; if 1.8 mL injection is more effective than 3.6 mL injection to increase the efficacy of IANB; and if supplementary buccal injection is able to increase the efficacy of IANB as compared to a negative control/placebo group. Data Sources: Randomized controlled clinical trials investigating different aspects (technique, premedication with anti-inflammatory drugs, different anesthetic agents) were searched. Success of IANB, as defined in the studies, was considered as the primary outcome. A meta-analysis was performed evaluating relative risks (RRs). Electronic databases (Medline, Embase, Cochrane Central) were searched after preparation of an appropriate search string. After application of selection criteria, a total of 37 studies were included; 19 of them were considered in the meta-analysis. There was evidence of a difference in favor of the use of premedication with anti-inflammatory drugs (RR, 1.80; CI 95%, 1.50-2.14; P

KW - Inferior alveolar nerve block

KW - Local anesthesia

KW - Pulpitis

KW - Systematic review

UR - http://www.scopus.com/inward/record.url?scp=85009347636&partnerID=8YFLogxK

U2 - 10.3290/j.qi.a37131

DO - 10.3290/j.qi.a37131

M3 - Article

AN - SCOPUS:85009347636

SN - 0033-6572

VL - 48

SP - 69

EP - 82

JO - QUINTESSENCE INTERNATIONAL

JF - QUINTESSENCE INTERNATIONAL

IS - 1

ER -